Interactor 1: ATG12 (P38316)
Ubiquitin-like protein ATG12 (Autophagy-related protein 12)
Gene: ATG12

Interactor 2: ATG5 (Q12380)
Autophagy protein 5
Gene: ATG5

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.96 1.00 0.985

The method score is based on:

Property Details
Experiments 11897782, 10688190, 11283351, 25461810, 11149920, 11139573, 9759731, 31399562, 34798055, 10406794, 23064152, 23238393, 14690591
Identification Methods coimmunoprecipitation, two hybrid, two hybrid pooling approach, pull down, affinity chromatography technology, biochemical, x-ray crystallography, anti tag coimmunoprecipitation, cosedimentation through density gradient, two hybrid array
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains APG12~APG5
Common GO terms GO:0000045 - autophagosome assembly
GO:0005829 - cytosol
GO:0008047 - enzyme activator activity
GO:0016236 - macroautophagy
GO:0032258 - cytoplasm to vacuole targeting by the Cvt pathway
and 5 others

more...

Homologous interactions 3

Homologous interactions

Color coding for hit scores

1 186
Sc

1 294
+ Hs
+ Mm
+ Sp

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Last updated: 15 Jul 2024