HitPredict

Interactor 1: SSH1 (P38353)
Sec sixty-one protein homolog (Ssh1 complex subunit SSH1) (Ssh1 complex subunit alpha)
Gene: SSH1

Interactor 2: SC6B2 (P52871)
Protein transport protein SBH2 (Ssh1 complex subunit SBH2) (Ssh1 complex subunit beta)
Gene: SBH2

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.67	1.00	0.821

Property	Details
Experiments	37968396, 23497013, 8612571
Identification Methods	affinity chromatography technology, protein complementation assay, anti bait coimmunoprecipitation
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	Plug_translocon~Sec61_beta, Sec61_beta~SecY
Common GO terms	GO:0005784 - Sec61 translocon complex GO:0005789 - endoplasmic reticulum membrane GO:0006614 - SRP-dependent cotranslational protein targeting to membrane GO:0006616 - SRP-dependent cotranslational protein targeting to membrane, translocation GO:0031204 - post-translational protein targeting to membrane, translocation and 1 others more... GO:0071261 - Ssh1 translocon complex
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1 490 Sc			1 88
+	Sc
		701506 SC61A_YEAST (1-470): 0: 561: 31.58		SC6B2_YEAST (1-88): 6.11e-43: 136: 100.00
+	Sc
		701505 SC61A_YEAST (1-470): 0: 561: 31.58		SC6B1_YEAST (1-83): 3.87e-30: 103: 55.42
+	Sc
		749041 SSH1_YEAST (1-490): 0: 558: 100.00		SC6B1_YEAST (1-83): 3.87e-30: 103: 55.42