HitPredict

Interactor 1: BRCA1 (P38398)
Breast cancer type 1 susceptibility protein (EC 2.3.2.27) (RING finger protein 53) (RING-type E3 ubiquitin transferase BRCA1)
Gene: BRCA1

Interactor 2: ELOA1 (Q14241)
Elongin-A (EloA) (Elongin 110 kDa subunit) (RNA polymerase II transcription factor SIII subunit A1) (SIII p110) (Transcription elongation factor B polypeptide 3)
Gene: ELOA

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.481

Property	Details
Experiments	25184681
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0006357 - regulation of transcription by RNA polymerase II
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 1863 Hs			1 772
+	Hs
		749592 BRCA1_HUMAN (1-1863): 0: 1570: 100.00		NIPBL_HUMAN (83-547): 3.75e-64: 235: 12.94
+	Hs
		749888 BRCA1_HUMAN (1-1863): 0: 1570: 100.00		MDN1_HUMAN (78-770): 1.6e-24: 112: 11.24
+	Hs
		749499 BRCA1_HUMAN (1-1863): 0: 1570: 100.00		MDC1_HUMAN (78-748): 1.57e-10: 67: 8.73
+	Hs
		749718 BRCA1_HUMAN (1-1863): 0: 1570: 100.00		TITIN_HUMAN (86-619): 3.12e-09: 63.1: 11.78
+	Hs
		584961 RO52_HUMAN (15-390): 2.55e-68: 241: 12.86		ELOA1_HUMAN (1-772): 1e-122: 388: 100.00
+	Hs
		1056907 TOPB1_HUMAN (1122-1861): 3.79e-150: 505: 14.12		MDC1_HUMAN (78-748): 1.57e-10: 67: 8.73
+	Hs
		1052010 BARD1_HUMAN (13-366): 4.46e-32: 137: 11.98		ELOA1_HUMAN (1-772): 1e-122: 388: 100.00
+	Hs
		1056954 BARD1_HUMAN (13-366): 4.46e-32: 137: 11.98		MDC1_HUMAN (78-748): 1.57e-10: 67: 8.73