HitPredict

Interactor 1: BRCA1 (P38398)
Breast cancer type 1 susceptibility protein (EC 2.3.2.27) (RING finger protein 53) (RING-type E3 ubiquitin transferase BRCA1)
Gene: BRCA1

Interactor 2: E2F4 (Q16254)
Transcription factor E2F4 (E2F-4)
Gene: E2F4

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.69 0.60 0.646

The method score is based on:

Property Details
Experiments 9244350, 21102443, 16357170
Identification Methods pull down, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0001216 - DNA-binding transcription activator activity
GO:0003677 - DNA binding
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0006357 - regulation of transcription by RNA polymerase II
and 1 others

more...
Homologous interactions 5

Homologous interactions

Color coding for hit scores

1 1863
Hs

1 413
+ Hs
+ Hs
+ Mm
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+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024