Interactor 1: IF5 (P38431)
Eukaryotic translation initiation factor 5 (eIF-5)
Gene: TIF5

Interactor 2: IF2P (P39730)
Eukaryotic translation initiation factor 5B (eIF-5B) (EC 3.6.5.3) (Translation initiation factor IF-2)
Gene: FUN12

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.73 1.00 0.855

The method score is based on:

Property Details
Experiments 11805826, 16429126, 37968396
Identification Methods tandem affinity purification, affinity chromatography technology
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains GTP_EFTU~eIF-5_eIF-2B
Common GO terms GO:0001732 - formation of cytoplasmic translation initiation complex
GO:0003743 - translation initiation factor activity
GO:0005525 - GTP binding
GO:0005829 - cytosol
GO:0006446 - regulation of translational initiation
and 3 others

more...

Homologous interactions 4

Homologous interactions

Color coding for hit scores

1 405
Sc

1 1002
+ Sc
+ Hs
+ Hv
+ Hv

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024