HitPredict

Interactor 1: NFSB (P38489)
Oxygen-insensitive NAD(P)H nitroreductase (EC 1.-.-.-) (Dihydropteridine reductase) (EC 1.5.1.34) (FMN-dependent nitroreductase)
Gene: NFSB

Interactor 2: NFSB (P38489)
Oxygen-insensitive NAD(P)H nitroreductase (EC 1.-.-.-) (Dihydropteridine reductase) (EC 1.5.1.34) (FMN-dependent nitroreductase)
Gene: NFSB

Species: Escherichia coli K-12

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	1.00	0.793

The method score is based on:

Property	Details
Experiments	24561554, 16858726
Identification Methods	two hybrid, blue native page, two hybrid array
Interaction Type	direct interaction, physical association

The annotation score is based on:

Property	Details
Interacting Pfam domains	Nitroreductase~Nitroreductase
Common GO terms	GO:0003955 - NAD(P)H dehydrogenase (quinone) activity GO:0004155 - 6,7-dihydropteridine reductase activity GO:0005829 - cytosol GO:0010181 - FMN binding GO:0016020 - membrane and 3 others more... GO:0042803 - protein homodimerization activity GO:0046256 - 2,4,6-trinitrotoluene catabolic process GO:0046857 - oxidoreductase activity, acting on other nitrogenous compounds as donors, with NAD or NADP as acceptor
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1	217
Ec

1	217

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024