HitPredict

Interactor 1: RFC3 (P38629)
Replication factor C subunit 3 (Replication factor C3) (Activator 1 40 kDa subunit)
Gene: RFC3

Interactor 2: ELG1 (Q12050)
Telomere length regulation protein ELG1 (Regulator of Ty1 transposition protein 110) (Telomere elongation suppressor ELG1)
Gene: ELG1

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.88	0.60	0.729

Property	Details
Experiments	12912927, 13678589, 37968396, 16554755, 30418970, 23499004
Identification Methods	coimmunoprecipitation, affinity chromatography technology, anti tag coimmunoprecipitation, tandem affinity purification
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003677 - DNA binding GO:0005634 - nucleus GO:0006261 - DNA-templated DNA replication GO:0007064 - mitotic sister chromatid cohesion GO:0031391 - Elg1 RFC-like complex and 1 others more... GO:0090618 - DNA clamp unloading
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 340 Sc			1 791
+	Hs
		721936 RFC5_HUMAN (8-338): 3.34e-86: 264: 49.40		RFC4_HUMAN (305-600): 3.63e-101: 318: 17.76
+	Sc
		751260 RFC3_YEAST (1-340): 2.34e-95: 288: 100.00		RFC1_YEAST (200-507): 4.07e-72: 254: 17.30
+	Sc
		751267 RFC3_YEAST (1-340): 2.34e-95: 288: 100.00		RFC4_YEAST (307-566): 3.22e-76: 251: 15.39
+	Sc
		751269 RFC3_YEAST (1-340): 2.34e-95: 288: 100.00		RFC2_YEAST (289-604): 4.87e-73: 244: 14.79
+	Hs
		722071 RFC5_HUMAN (8-338): 3.34e-86: 264: 49.40		RFC2_HUMAN (290-547): 2.2e-75: 250: 14.91
+	Hs
		721933 RFC4_HUMAN (3-332): 3.98e-83: 258: 34.62		RFC2_HUMAN (290-547): 2.2e-75: 250: 14.91
+	At
		1275801 RFC5_ARATH (8-338): 2.38e-80: 251: 44.64		RFC4_ARATH (305-596): 8.36e-75: 248: 12.54
+	Zm
		75542 B4FJC2_MAIZE (11-339): 2.25e-80: 250: 43.98		B4FQT5_MAIZE (305-604): 3.74e-73: 243: 12.50
+	At
		1321531 RFC5_ARATH (8-338): 2.38e-80: 251: 44.64		RFC2_ARATH (308-529): 2.58e-71: 238: 14.23
+	Sc
		751278 RFC3_YEAST (1-340): 2.34e-95: 288: 100.00		CTF18_YEAST (198-539): 2.53e-53: 199: 14.60
+	Hs
		722179 RFC5_HUMAN (8-338): 3.34e-86: 264: 49.40		RFC1_HUMAN (227-523): 2.12e-54: 205: 14.56
+	Hs
		721934 RFC4_HUMAN (3-332): 3.98e-83: 258: 34.62		RFC1_HUMAN (227-523): 2.12e-54: 205: 14.56
+	Dm
		725336 Q9VKW3_DROME (4-337): 2.69e-80: 249: 45.83		RFC1_DROME (122-516): 3.35e-53: 201: 15.88
+	Hs
		777901 RFC5_HUMAN (8-338): 3.34e-86: 264: 49.40		CTF18_HUMAN (240-573): 1.7e-46: 181: 13.50
+	Sp
		144039 RFC3_SCHPO (1-339): 2.26e-84: 260: 51.33		ELG1_SCHPO (240-524): 8.17e-48: 184: 21.96
+	Hs
		722015 RFC4_HUMAN (3-332): 3.98e-83: 258: 34.62		CTF18_HUMAN (240-573): 1.7e-46: 181: 13.50
+	Hs
		777906 RFC5_HUMAN (8-338): 3.34e-86: 264: 49.40		ATAD5_HUMAN (348-510): 1.29e-37: 154: 23.67
+	Hs
		722022 RFC4_HUMAN (3-332): 3.98e-83: 258: 34.62		ATAD5_HUMAN (348-510): 1.29e-37: 154: 23.67