Protein: AUXI
Auxilin (EC 3.1.3.-) (DnaJ homolog subfamily C member 6)

Gene: AUXI, DNAJC6
Organism: Homo sapiens
Interactions: 59
UniProt ID: O75061

Gene Ontology (top 5):
GO:0004725 - protein tyrosine phosphatase activity
GO:0005829 - cytosol
GO:0014069 - postsynaptic density
GO:0016191 - synaptic vesicle uncoating
GO:0017124 - SH3 domain binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

171639

GAK
Cyclin-G-associated kinase

1

13

High-throughput

0.691

High

269940

GNAT1
Guanine nucleotide-binding protein G(t) subunit alpha-1

2

4

High-throughput

0.621

High

269965

TENS3
Tensin-3

1

13

High-throughput

0.618

High

269936

CLCA
Clathrin light chain A

2

3

High-throughput

0.611

High

269969

AP2M1
AP-2 complex subunit mu

2

3

High-throughput

0.611

High

269954

CLH1
Clathrin heavy chain 1

2

6

Small-scale

0.595

High

269976

ILRL2
Interleukin-1 receptor-like 2

2

3

High-throughput

0.574

High

269966

LZTR1
Leucine-zipper-like transcriptional regulator 1

2

2

High-throughput

0.558

High

269939

TAU
Microtubule-associated protein tau

2

4

High-throughput

0.552

High

130899

HIP1
Huntingtin-interacting protein 1

1

7

High-throughput

0.536

High

135855

P3C2A
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha

1

1

High-throughput

0.536

High

269937

CLCB
Clathrin light chain B

1

3

High-throughput

0.536

High

269948

EPS15
Epidermal growth factor receptor substrate 15

1

3

High-throughput

0.536

High

269950

HXK3
Hexokinase-3

1

1

High-throughput

0.536

High

269951

CLH2
Clathrin heavy chain 2

1

6

High-throughput

0.536

High

269955

PICAL
Phosphatidylinositol-binding clathrin assembly protein

1

7

High-throughput

0.536

High

269956

HDAC1
Histone deacetylase 1

1

4

High-throughput

0.536

High

269958

EPN4
Clathrin interactor 1

1

4

High-throughput

0.536

High

269960

RBP1
RalA-binding protein 1

1

7

High-throughput

0.536

High

269970

REPS1
RalBP1-associated Eps domain-containing protein 1

1

4

High-throughput

0.536

High

269977

BMP2K
BMP-2-inducible protein kinase

1

5

High-throughput

0.536

High

269983

VPP2
V-type proton ATPase 116 kDa subunit a 2

1

1

High-throughput

0.536

High

269972

GCP5
Gamma-tubulin complex component 5

1

0

High-throughput

0.513

High

269979

VTI1B
Vesicle transport through interaction with t-SNAREs homolog 1B

1

0

High-throughput

0.513

High

269935

BAG2
BAG family molecular chaperone regulator 2

1

2

High-throughput

0.508

High

269957

GBX1
Homeobox protein GBX-1

1

3

High-throughput

0.489

High

269975

PAAT
ATPase PAAT

1

1

High-throughput

0.489

High

269978

GULP1
PTB domain-containing engulfment adapter protein 1

1

5

High-throughput

0.489

High

269981

MYH13
Myosin-13

1

2

High-throughput

0.489

High

229909

SAHH2
S-adenosylhomocysteine hydrolase-like protein 1

1

4

High-throughput

0.479

High

269718

CAPON
Carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein

1

4

High-throughput

0.479

High

269933

PCNT
Pericentrin

1

7

High-throughput

0.479

High

269934

AP2A1
AP-2 complex subunit alpha-1

1

5

High-throughput

0.479

High

269944

MK01
Mitogen-activated protein kinase 1

1

2

High-throughput

0.479

High

269945

2AAA
Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform

1

4

High-throughput

0.479

High

269952

PPIA
Peptidyl-prolyl cis-trans isomerase A

1

3

High-throughput

0.479

High

269953

AP2B1
AP-2 complex subunit beta

1

7

High-throughput

0.479

High

269959

ABRX2
BRISC complex subunit Abraxas 2

1

2

High-throughput

0.479

High

269961

MARE1
Microtubule-associated protein RP/EB family member 1

1

2

High-throughput

0.479

High

269963

PP6R3
Serine/threonine-protein phosphatase 6 regulatory subunit 3

1

4

High-throughput

0.479

High

269967

PAF1
RNA polymerase II-associated factor 1 homolog

1

2

High-throughput

0.479

High

269968

SMAP2
Stromal membrane-associated protein 2

1

2

High-throughput

0.479

High

269973

WDR11
WD repeat-containing protein 11

1

1

High-throughput

0.479

High

269982

CP131
Centrosomal protein of 131 kDa

1

5

High-throughput

0.479

High

269943

PEX2
Peroxisome biogenesis factor 2

1

0

High-throughput

0.458

High

269947

STAT1
Signal transducer and activator of transcription 1-alpha/beta

1

0

Small-scale

0.458

High

269971

SYGP1
Ras/Rap GTPase-activating protein SynGAP

1

1

High-throughput

0.445

High

104930

APRIO
Alternative prion protein

1

4

High-throughput

0.437

High

246328

KDM1A
Lysine-specific histone demethylase 1A

1

1

High-throughput

0.437

High

269932

MPPB
Mitochondrial-processing peptidase subunit beta

1

4

High-throughput

0.437

High

269938

DLDH
Dihydrolipoyl dehydrogenase, mitochondrial

1

2

High-throughput

0.437

High

269942

RFA2
Replication protein A 32 kDa subunit

1

2

High-throughput

0.437

High

269946

SDHA
Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial

1

1

High-throughput

0.437

High

269949

LPPRC
Leucine-rich PPR motif-containing protein, mitochondrial

1

3

High-throughput

0.437

High

269962

P3H1
Prolyl 3-hydroxylase 1

1

2

High-throughput

0.437

High

269964

KANK2
KN motif and ankyrin repeat domain-containing protein 2

1

4

High-throughput

0.437

High

269980

RCOR1
REST corepressor 1

1

1

High-throughput

0.437

High

269941

CX6A1
Cytochrome c oxidase subunit 6A1, mitochondrial

1

0

High-throughput

0.279

Low

269974

GCP60
Golgi resident protein GCP60

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025