HitPredict

Interactor 1: RFC3 (P38629)
Replication factor C subunit 3 (Replication factor C3) (Activator 1 40 kDa subunit)
Gene: RFC3

Interactor 2: RUVB2 (Q12464)
RuvB-like protein 2 (RUVBL2) (EC 3.6.4.12) (TIP49-homology protein 2) (TIP49b homolog)
Gene: RVB2

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.58	1.00	0.767

Property	Details
Experiments	11805837, 26831523
Identification Methods	anti tag coimmunoprecipitation, affinity chromatography technology
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	AAA~TIP49
Common GO terms	GO:0005524 - ATP binding GO:0005634 - nucleus GO:0006281 - DNA repair GO:0016887 - ATP hydrolysis activity
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 340 Sc			1 471
+	Mm
		1321946 RFC5_MOUSE (9-338): 2.32e-87: 268: 48.64		RUVB2_MOUSE (4-451): 0: 680: 68.15
+	Hs
		777947 RFC5_HUMAN (8-338): 3.34e-86: 264: 49.40		RUVB2_HUMAN (4-451): 0: 680: 68.15
+	Sc
		772446 RFC2_YEAST (1-329): 5.33e-75: 236: 32.26		RUVB2_YEAST (1-471): 0: 707: 100.00
+	Hs
		722060 RFC4_HUMAN (3-332): 3.98e-83: 258: 34.62		RUVB2_HUMAN (4-451): 0: 680: 68.15
+	Sc
		772279 RFC4_YEAST (12-333): 2.2e-72: 229: 34.06		RUVB2_YEAST (1-471): 0: 707: 100.00
+	Sc
		747133 RFC5_YEAST (14-332): 9.6e-71: 225: 21.97		RUVB2_YEAST (1-471): 0: 707: 100.00
+	Mm
		888115 RFC5_MOUSE (9-338): 2.32e-87: 268: 48.64		RUVB1_MOUSE (10-448): 0: 658: 41.72
+	Sc
		751287 RFC3_YEAST (1-340): 2.34e-95: 288: 100.00		RUVB1_YEAST (8-448): 0: 624: 41.10
+	Sc
		772435 RFC2_YEAST (1-329): 5.33e-75: 236: 32.26		RUVB1_YEAST (8-448): 0: 624: 41.10
+	Sc
		772266 RFC4_YEAST (12-333): 2.2e-72: 229: 34.06		RUVB1_YEAST (8-448): 0: 624: 41.10
+	Sc
		747120 RFC5_YEAST (14-332): 9.6e-71: 225: 21.97		RUVB1_YEAST (8-448): 0: 624: 41.10