Protein: TKT1
Transketolase 1 (TK 1) (EC 2.2.1.1)

Gene: TKT1, TKL1
Organism: Saccharomyces cerevisiae S288C
Interactions: 80
UniProt ID: P23254

Gene Ontology (top 5):
GO:0004802 - transketolase activity
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0006098 - pentose-phosphate shunt
GO:0046872 - metal ion binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

655565

TKT2
Transketolase 2

5

17

High-throughput

0.911

High

655555

TKT1
Transketolase 1

2

16

Small-scale

0.757

High

655576

RSP5
E3 ubiquitin-protein ligase RSP5

2

4

Small-scale

0.602

High

655577

SSB2
Ribosome-associated molecular chaperone SSB2

2

6

High-throughput

0.601

High

509405

UBI4P
Polyubiquitin [Cleaved into: Ubiquitin]

2

4

Small-scale

0.571

High

543860

SSB1
Ribosome-associated molecular chaperone SSB1

2

6

High-throughput

0.571

High

655585

RPN11
Ubiquitin carboxyl-terminal hydrolase RPN11

2

0

High-throughput

0.559

High

523100

HSP71
Heat shock protein SSA1

2

4

High-throughput

0.552

High

655556

SIS1
Protein SIS1

1

4

High-throughput

0.515

High

655570

YLF2
Obg-like ATPase homolog

1

2

High-throughput

0.515

High

651901

ESS1
Peptidyl-prolyl cis-trans isomerase ESS1

1

1

High-throughput

0.501

High

655588

SET2
Histone-lysine N-methyltransferase, H3 lysine-36 specific

1

5

High-throughput

0.501

High

655589

PTK2
Serine/threonine-protein kinase PTK2/STK2

1

1

High-throughput

0.501

High

628040

FKBP
FK506-binding protein 1

1

6

High-throughput

0.500

High

655581

EGH1
Ergosteryl-beta-glucosidase

1

0

High-throughput

0.493

High

655591

ACS2
Acetyl-coenzyme A synthetase 2

1

0

High-throughput

0.493

High

655584

WWM1
WW domain-containing protein WWM1

1

0

High-throughput

0.480

High

655575

RV167
Reduced viability upon starvation protein 167

1

0

High-throughput

0.479

High

358968

G3P2
Glyceraldehyde-3-phosphate dehydrogenase 2

1

2

High-throughput

0.479

High

361419

SODC
Superoxide dismutase [Cu-Zn]

1

1

High-throughput

0.479

High

365564

PGK
Phosphoglycerate kinase

1

2

High-throughput

0.479

High

367697

ENO1
Enolase 1

1

3

High-throughput

0.479

High

367899

ENO2
Enolase 2

1

3

High-throughput

0.479

High

368595

PMG1
Phosphoglycerate mutase 1

1

2

High-throughput

0.479

High

392256

HSP82
ATP-dependent molecular chaperone HSP82

1

4

High-throughput

0.479

High

439247

PDC1
Pyruvate decarboxylase isozyme 1

1

1

High-throughput

0.479

High

555010

G6PI
Glucose-6-phosphate isomerase

1

1

High-throughput

0.479

High

575892

CYPH
Peptidyl-prolyl cis-trans isomerase

1

1

High-throughput

0.479

High

578876

HSC82
ATP-dependent molecular chaperone HSC82

1

4

High-throughput

0.479

High

594198

RPB3
DNA-directed RNA polymerase II subunit RPB3

1

1

High-throughput

0.479

High

655559

HS104
Heat shock protein 104

1

1

High-throughput

0.479

High

655564

PRS6A
26S proteasome regulatory subunit 6A

1

4

High-throughput

0.479

High

655566

TCTP
Translationally-controlled tumor protein homolog

1

1

High-throughput

0.479

High

655569

6PGD1
6-phosphogluconate dehydrogenase, decarboxylating 1

1

1

High-throughput

0.479

High

655571

RPN1
26S proteasome regulatory subunit RPN1

1

1

High-throughput

0.479

High

655573

DHH1
ATP-dependent RNA helicase DHH1

1

2

High-throughput

0.479

High

655583

OTU1
Ubiquitin thioesterase OTU1

1

1

High-throughput

0.479

High

655593

UBP10
Ubiquitin carboxyl-terminal hydrolase 10

1

2

High-throughput

0.479

High

655597

TOM1
E3 ubiquitin-protein ligase TOM1

1

4

High-throughput

0.479

High

364936

KPYK1
Pyruvate kinase 1

1

0

High-throughput

0.458

High

368409

TPIS
Triosephosphate isomerase

1

0

High-throughput

0.458

High

416373

HXKA
Hexokinase-1

1

0

High-throughput

0.458

High

450707

KAD2
Adenylate kinase

1

0

High-throughput

0.458

High

481855

SYIC
Isoleucine--tRNA ligase, cytoplasmic

1

0

High-throughput

0.458

High

558589

CAF20
Cap-associated protein CAF20

1

0

High-throughput

0.458

High

572517

ALF
Fructose-bisphosphate aldolase

1

0

High-throughput

0.458

High

578213

TAL1
Transaldolase

1

0

High-throughput

0.458

High

655560

RPC3
DNA-directed RNA polymerase III subunit RPC3

1

0

High-throughput

0.458

High

655562

SMY2
Protein SMY2

1

0

High-throughput

0.458

High

655572

RPN10
26S proteasome regulatory subunit RPN10

1

0

High-throughput

0.458

High

655574

LAA1
AP-1 accessory protein LAA1

1

0

High-throughput

0.458

High

655592

PIL1
Sphingolipid long chain base-responsive protein PIL1

1

0

High-throughput

0.458

High

655596

COFI
Cofilin

1

0

High-throughput

0.458

High

655602

VAM6
Vacuolar morphogenesis protein 6

1

0

High-throughput

0.458

High

655557

MAS5
Mitochondrial protein import protein MAS5

1

3

High-throughput

0.445

High

655561

HSP7F
Heat shock protein homolog SSE1

1

6

High-throughput

0.445

High

655580

MPH1
ATP-dependent DNA helicase MPH1

1

3

Small-scale

0.439

High

655558

TF2B
Transcription initiation factor IIB

1

1

High-throughput

0.437

High

655606

RRP6
Exosome complex exonuclease RRP6

1

1

High-throughput

0.437

High

655607

SMT3
Ubiquitin-like protein SMT3

1

2

High-throughput

0.437

High

655608

DBP10
ATP-dependent RNA helicase DBP10

1

4

High-throughput

0.437

High

655587

PFD1
Prefoldin subunit 1

1

0

High-throughput

0.426

High

655590

PFD6
Prefoldin subunit 6

1

0

High-throughput

0.426

High

655594

PFD4
Prefoldin subunit 4

1

0

High-throughput

0.426

High

655578

TCPE
T-complex protein 1 subunit epsilon

1

3

High-throughput

0.407

High

655586

FIP1
Pre-mRNA polyadenylation factor FIP1

1

0

High-throughput

0.279

Low

655563

PRP40
Pre-mRNA-processing protein PRP40

1

0

High-throughput

0.261

Low

655601

URN1
Pre-mRNA-splicing factor URN1

1

0

High-throughput

0.261

Low

655567

NU170
Nucleoporin NUP170

1

0

High-throughput

0.249

Low

655568

YGP1
Protein YGP1

1

0

High-throughput

0.249

Low

655579

FIS1
Mitochondrial fission 1 protein

1

0

Small-scale

0.249

Low

655582

DSN1
Kinetochore-associated protein DSN1

1

0

High-throughput

0.249

Low

655595

SAM50
Sorting assembly machinery 50 kDa subunit

1

0

High-throughput

0.249

Low

655598

RUVB1
RuvB-like protein 1

1

0

High-throughput

0.249

Low

655599

POB3
FACT complex subunit POB3

1

0

High-throughput

0.249

Low

655600

MMS22
E3 ubiquitin-protein ligase substrate receptor MMS22

1

0

High-throughput

0.249

Low

655603

ZEO1
Protein ZEO1

1

0

High-throughput

0.249

Low

655604

AP3D
AP-3 complex subunit delta

1

0

High-throughput

0.249

Low

655605

ATG9
Autophagy-related protein 9

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025