HitPredict

Interactor 1: HSE1 (P38753)
Class E vacuolar protein-sorting machinery protein HSE1
Gene: HSE1

Interactor 2: RSP5 (P39940)
E3 ubiquitin-protein ligase RSP5 (EC 2.3.2.26) (HECT-type E3 ubiquitin transferase RSP5) (Reverses SPT-phenotype protein 5)
Gene: RSP5

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.65 0.60 0.625

The method score is based on:

Property Details
Experiments 15086794, 17079730
Identification Methods two hybrid, affinity chromatography technology, pull down
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0010008 - endosome membrane
GO:0035091 - phosphatidylinositol binding
GO:0043130 - ubiquitin binding
GO:0043162 - ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 452
Sc

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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024