HitPredict

Interactor 1: RPN1 (P38764)
26S proteasome regulatory subunit RPN1 (HMG-CoA reductase degradation protein 2) (Proteasome non-ATPase subunit 1)
Gene: RPN1

Interactor 2: PRS8 (Q01939)
26S proteasome regulatory subunit 8 homolog (Protein CIM3) (Protein SUG1) (Tat-binding protein TBY1)
Gene: RPT6

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.96 1.00 0.983

The method score is based on:

Property Details
Experiments 10688918, 16554755, 31487956, 23900548, 37968396, 10873636, 9741626, 9584156, 16429126, 19289793, 19446323, 21658604, 22237024, 22940862, 14759368
Identification Methods affinity chromatography technology, pull down, biochemical, tandem affinity purification, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains AAA_lid_3~RPN1_C, AAA_lid_3~RPN1_RPN2_N
Common GO terms GO:0000502 - proteasome complex
GO:0005634 - nucleus
GO:0008540 - proteasome regulatory particle, base subcomplex
GO:0034515 - proteasome storage granule
GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 993
Sc

1 405
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Last updated: 15 Jul 2024