Protein: CKS2
Cyclin-dependent kinases regulatory subunit 2 (CKS-2)

Gene: CKS2
Organism: Homo sapiens
Interactions: 49
UniProt ID: P33552

Gene Ontology (top 5):
GO:0000307 - cyclin-dependent protein kinase holoenzyme complex
GO:0003682 - chromatin binding
GO:0006357 - regulation of transcription by RNA polymerase II
GO:0007127 - meiosis I
GO:0007346 - regulation of mitotic cell cycle

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

443221

CDK1
Cyclin-dependent kinase 1

12

20

Small-scale

0.981

High

667577

CDK2
Cyclin-dependent kinase 2

8

20

Small-scale

0.971

High

753913

CDK3
Cyclin-dependent kinase 3

5

20

High-throughput

0.926

High

753927

PMYT1
Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase

4

5

High-throughput

0.813

High

753909

CKS1
Cyclin-dependent kinases regulatory subunit 1

2

5

High-throughput

0.811

High

573763

CCNB1
G2/mitotic-specific cyclin-B1

6

20

Small-scale

0.735

High

753923

KCC1D
Calcium/calmodulin-dependent protein kinase type 1D

3

0

High-throughput

0.720

High

629071

CCNA2
Cyclin-A2

5

20

Small-scale

0.714

High

753937

FZR1
Fizzy-related protein homolog

4

6

High-throughput

0.691

High

325469

CCNB2
G2/mitotic-specific cyclin-B2

3

20

Small-scale

0.670

High

284290

GEMI
Geminin

2

1

High-throughput

0.628

High

666951

CCNE1
G1/S-specific cyclin-E1

2

20

High-throughput

0.628

High

753907

CDN1B
Cyclin-dependent kinase inhibitor 1B

2

3

High-throughput

0.628

High

753931

CDT1
DNA replication factor Cdt1

2

1

High-throughput

0.628

High

753933

IKZF5
Zinc finger protein Pegasus

2

3

High-throughput

0.628

High

753908

CDK9
Cyclin-dependent kinase 9

1

16

High-throughput

0.618

High

753914

CDK5
Cyclin-dependent kinase 5

1

20

High-throughput

0.618

High

753936

CDK12
Cyclin-dependent kinase 12

1

16

High-throughput

0.618

High

753905

CDN1A
Cyclin-dependent kinase inhibitor 1

2

3

High-throughput

0.611

High

753922

SPDYC
Speedy protein C

2

5

High-throughput

0.601

High

753904

CKS2
Cyclin-dependent kinases regulatory subunit 2

1

5

Small-scale

0.575

High

753911

EF1A1
Elongation factor 1-alpha 1

1

2

High-throughput

0.541

High

66874

SPDE4
Speedy protein E4

1

5

High-throughput

0.536

High

651117

CCNO
Cyclin-O

1

20

High-throughput

0.536

High

753917

CDC20
Cell division cycle protein 20 homolog

1

6

High-throughput

0.536

High

753910

GRB2
Growth factor receptor-bound protein 2

1

0

High-throughput

0.518

High

753928

NPAS1
Neuronal PAS domain-containing protein 1

1

0

High-throughput

0.513

High

753912

CCNA1
Cyclin-A1

1

20

Small-scale

0.501

High

753916

SSBP
Single-stranded DNA-binding protein, mitochondrial

1

1

Small-scale

0.501

High

753919

CDC37
Hsp90 co-chaperone Cdc37

1

1

Small-scale

0.501

High

753934

PKHG2
Pleckstrin homology domain-containing family G member 2

1

1

High-throughput

0.489

High

753915

KMT2A
Histone-lysine N-methyltransferase 2A

1

1

Small-scale

0.479

High

413285

P53
Cellular tumor antigen p53

1

0

High-throughput

0.458

High

450932

LDHB
L-lactate dehydrogenase B chain

1

1

Small-scale

0.457

High

461196

HS90A
Heat shock protein HSP 90-alpha

1

3

Small-scale

0.457

High

753921

SPDE7
Putative speedy protein E7

1

5

High-throughput

0.445

High

753920

SMTL2
Smoothelin-like protein 2

1

1

High-throughput

0.407

High

753924

LACC1
Purine nucleoside phosphorylase LACC1

3

0

High-throughput

0.347

High

753926

GA2L1
GAS2-like protein 1

2

0

High-throughput

0.328

High

399550

VTNC
Vitronectin

1

0

High-throughput

0.282

High

753918

U119A
Protein unc-119 homolog A

1

0

High-throughput

0.282

High

753938

T22D4
TSC22 domain family protein 4

1

0

High-throughput

0.282

High

753925

PTGR3
Prostaglandin reductase 3

1

0

High-throughput

0.279

Low

753929

DHRS6
Dehydrogenase/reductase SDR family member 6

1

0

High-throughput

0.279

Low

753930

UBXN6
UBX domain-containing protein 6

1

0

High-throughput

0.279

Low

753932

GO45
Golgin-45

1

0

High-throughput

0.265

Low

753906

PERI
Peripherin

1

0

High-throughput

0.249

Low

753935

LMBD1
Lysosomal cobalamin transport escort protein LMBD1

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025