Protein: SPDE4
Speedy protein E4

Gene: SPDE4, SPDYE4
Organism: Homo sapiens
Interactions: 61
UniProt ID: A6NLX3

Gene Ontology (top 5):
GO:0019901 - protein kinase binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

66883

CDK5
Cyclin-dependent kinase 5

3

17

High-throughput

0.768

High

66882

CDK3
Cyclin-dependent kinase 3

2

17

High-throughput

0.700

High

66878

CDK9
Cyclin-dependent kinase 9

1

17

High-throughput

0.691

High

66879

CKS1
Cyclin-dependent kinases regulatory subunit 1

3

5

High-throughput

0.665

High

66863

CDK1
Cyclin-dependent kinase 1

1

17

High-throughput

0.640

High

66868

CDK2
Cyclin-dependent kinase 2

1

17

High-throughput

0.640

High

66884

CDK16
Cyclin-dependent kinase 16

1

17

High-throughput

0.618

High

66876

SYQ
Glutamine--tRNA ligase

2

0

High-throughput

0.580

High

66859

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

0

High-throughput

0.578

High

66874

CKS2
Cyclin-dependent kinases regulatory subunit 2

1

5

High-throughput

0.536

High

66899

DNJA3
DnaJ homolog subfamily A member 3, mitochondrial

1

1

High-throughput

0.536

High

66866

CCNB1
G2/mitotic-specific cyclin-B1

1

0

High-throughput

0.513

High

66856

BRD4
Bromodomain-containing protein 4

1

5

High-throughput

0.506

High

66869

BRD2
Bromodomain-containing protein 2

1

6

High-throughput

0.506

High

66885

SKP2
S-phase kinase-associated protein 2

1

1

High-throughput

0.506

High

66887

BRD3
Bromodomain-containing protein 3

1

6

High-throughput

0.506

High

66872

DNJA1
DnaJ homolog subfamily A member 1

1

1

High-throughput

0.489

High

66853

B4DEF8
Large ribosomal subunit protein mL45

1

1

High-throughput

0.437

High

66888

PWP2
Periodic tryptophan protein 2 homolog

1

1

High-throughput

0.437

High

66909

WDR3
WD repeat-containing protein 3

1

1

High-throughput

0.437

High

66901

RM45
Large ribosomal subunit protein mL45

1

1

High-throughput

0.407

High

66857

UBP2
Ubiquitin carboxyl-terminal hydrolase 2

2

0

High-throughput

0.316

High

66875

HXK4
Hexokinase-4

2

0

High-throughput

0.316

High

66896

GPKOW
G-patch domain and KOW motifs-containing protein

2

0

High-throughput

0.316

High

66898

MGN2
Protein mago nashi homolog 2

2

0

High-throughput

0.316

High

66900

NTAQ1
Protein N-terminal glutamine amidohydrolase

2

0

High-throughput

0.316

High

66903

TBC13
TBC1 domain family member 13

2

0

High-throughput

0.316

High

66910

PPIL1
Peptidyl-prolyl cis-trans isomerase-like 1

2

0

High-throughput

0.316

High

66897

UBP7
Ubiquitin carboxyl-terminal hydrolase 7

1

0

High-throughput

0.289

High

66854

Z587B
Zinc finger protein 587B

1

0

High-throughput

0.279

Low

66860

GBA1
Lysosomal acid glucosylceramidase

1

0

High-throughput

0.279

Low

66861

A4
Amyloid-beta precursor protein

1

0

High-throughput

0.279

Low

66862

AGAL
Alpha-galactosidase A

1

0

High-throughput

0.279

Low

66864

CATB
Cathepsin B

1

0

High-throughput

0.279

Low

66865

CN37
2',3'-cyclic-nucleotide 3'-phosphodiesterase

1

0

High-throughput

0.279

Low

66870

DNMT1
DNA

1

0

High-throughput

0.279

Low

66871

TYK2
Non-receptor tyrosine-protein kinase TYK2

1

0

High-throughput

0.279

Low

66877

GUAA
GMP synthase [glutamine-hydrolyzing]

1

0

High-throughput

0.279

Low

66880

SKP1
S-phase kinase-associated protein 1

1

0

High-throughput

0.279

Low

66881

ACTC
Actin, alpha cardiac muscle 1

1

0

High-throughput

0.279

Low

66886

EXOS2
Exosome complex component RRP4

1

0

High-throughput

0.279

Low

66889

RSU1
Ras suppressor protein 1

1

0

High-throughput

0.279

Low

66890

ERC6L
DNA excision repair protein ERCC-6-like

1

0

High-throughput

0.279

Low

66893

DCXR
L-xylulose reductase

1

0

High-throughput

0.279

Low

66894

SLN11
Schlafen family member 11

1

0

High-throughput

0.279

Low

66904

QPCTL
Glutaminyl-peptide cyclotransferase-like protein

1

0

High-throughput

0.279

Low

66906

NDUF4
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 4

1

0

High-throughput

0.279

Low

66908

AKP8L
A-kinase anchor protein 8-like

1

0

High-throughput

0.279

Low

66911

HBS1L
HBS1-like protein

1

0

High-throughput

0.279

Low

66912

ORC6
Origin recognition complex subunit 6

1

0

High-throughput

0.279

Low

66855

SPT5H
Transcription elongation factor SPT5

1

0

High-throughput

0.249

Low

66858

KDM4B
Lysine-specific demethylase 4B

1

0

High-throughput

0.249

Low

66867

TAF1
Transcription initiation factor TFIID subunit 1

1

0

High-throughput

0.249

Low

66873

STIP1
Stress-induced-phosphoprotein 1

1

0

High-throughput

0.249

Low

66891

BCORL
BCL-6 corepressor-like protein 1

1

0

High-throughput

0.249

Low

66892

CDCA2
Cell division cycle-associated protein 2

1

0

High-throughput

0.249

Low

66895

MORC4
MORC family CW-type zinc finger protein 4

1

0

High-throughput

0.249

Low

66902

ANLN
Anillin

1

0

High-throughput

0.249

Low

66905

AATF
Protein AATF

1

0

High-throughput

0.249

Low

66907

NXF1
Nuclear RNA export factor 1

1

0

High-throughput

0.249

Low

46400

A0A1W2PQS6
Small ribosomal subunit protein eS10

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025