HitPredict

Interactor 1: VPS41 (P38959)
Vacuolar protein sorting-associated protein 41 (Vacuolar morphogenesis protein 2)
Gene: VPS41

Interactor 2: AP3D (Q08951)
AP-3 complex subunit delta (Adaptor-related protein complex 3 subunit delta) (Delta-adaptin 3) (Delta-adaptin)
Gene: APL5

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.87	0.60	0.726

Property	Details
Experiments	10559961, 11160821, 32840906, 19741093, 21079247
Identification Methods	affinity chromatography technology, two hybrid, pull down, proximity labelling technology
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0006623 - protein targeting to vacuole
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 992 Sc			1 932
+	Hs
		150187 VPS41_HUMAN (70-982): 0: 807: 24.00		AP3D1_HUMAN (21-919): 1.98e-151: 479: 26.50
+	Rn
		78224 D3ZVH6_RAT (99-952): 0: 752: 22.40		B5DFK6_RAT (21-917): 1.14e-150: 478: 26.56
+	Sc
		991326 VAM6_YEAST (605-983): 3.89e-66: 243: 10.90		AP3D_YEAST (1-932): 0: 626: 100.00
+	Hs
		150254 VPS39_HUMAN (510-982): 3.4e-110: 363: 14.26		AP3D1_HUMAN (21-919): 1.98e-151: 479: 26.50
+	Sc
		991335 VAM6_YEAST (605-983): 3.89e-66: 243: 10.90		AP1G1_YEAST (25-721): 7.34e-73: 259: 18.48
+	Sc
		743411 VAM6_YEAST (605-983): 3.89e-66: 243: 10.90		AP2A_YEAST (25-820): 1.96e-48: 188: 17.17