HitPredict

Interactor 1: DYN1 (P39055)
Dynamin (EC 3.6.5.5)
Gene: dyn-1

Interactor 2: Q09989 (Q09989)
SH3 domain-containing protein
Gene: sdpn-1

Species: Caenorhabditis elegans

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.34	1.00	0.590

Property	Details
Experiments	23549480
Identification Methods	two hybrid
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PH~SH3_1
Common GO terms	GO:0005737 - cytoplasm GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 830 Ce			1 489
+	Ce
		760501 DYN1_CAEEL (1-762): 0: 986: 100.00		Q6AHQ8_CAEEL (1-489): 1.48e-94: 297: 100.00
+	Hs
		983417 DYN1_HUMAN (5-820): 0: 996: 62.07		PACN2_HUMAN (1-486): 1.71e-84: 270: 29.98
+	Mm
		760487 DYN2_MOUSE (5-830): 0: 986: 63.59		PACN2_MOUSE (1-486): 1.09e-87: 279: 29.57
+	Mm
		1142989 DYN3_MOUSE (5-830): 0: 1001: 63.76		PACN1_MOUSE (2-485): 1.43e-74: 243: 27.84
+	Hs
		983406 DYN1_HUMAN (5-820): 0: 996: 62.07		PACN1_HUMAN (1-485): 3.05e-76: 247: 27.98
+	Mm
		760451 DYN1_MOUSE (5-826): 0: 995: 62.05		PACN1_MOUSE (2-485): 1.43e-74: 243: 27.84
+	Rn
		599414 DYN1_RAT (5-820): 0: 991: 62.31		PACN1_RAT (2-485): 2.24e-75: 245: 28.25
+	Rn
		996551 DYN3_RAT (5-830): 0: 988: 62.66		PACN1_RAT (2-485): 2.24e-75: 245: 28.25
+	Mm
		760475 DYN2_MOUSE (5-830): 0: 986: 63.59		PACN1_MOUSE (2-485): 1.43e-74: 243: 27.84
+	Hs
		983372 DYN1_HUMAN (5-820): 0: 996: 62.07		MYO1E_HUMAN (44-482): 9.45e-59: 211: 16.63
+	Hs
		983416 DYN1_HUMAN (5-820): 0: 996: 62.07		PACN3_HUMAN (2-312): 1.42e-57: 198: 29.90
+	Mm
		760485 DYN2_MOUSE (5-830): 0: 986: 63.59		PACN3_MOUSE (2-312): 4.04e-58: 200: 30.55
+	Hs
		983392 DYN1_HUMAN (5-820): 0: 996: 62.07		NOSTN_HUMAN (16-489): 2.18e-50: 181: 15.40
+	Hs
		983403 DYN1_HUMAN (5-820): 0: 996: 62.07		FNBP1_HUMAN (11-473): 1.49e-40: 156: 14.00
+	Hs
		1301542 DYN3_HUMAN (5-830): 0: 987: 62.43		FNBP1_HUMAN (11-473): 1.49e-40: 156: 14.00
+	Mm
		760473 DYN2_MOUSE (5-830): 0: 986: 63.59		SRC8_MOUSE (153-486): 2.87e-39: 151: 16.77
+	Mm
		760469 DYN1_MOUSE (5-826): 0: 995: 62.05		ITSN1_MOUSE (48-488): 2.77e-15: 81: 12.30
+	Rn
		599413 DYN1_RAT (5-820): 0: 991: 62.31		ITSN1_RAT (48-488): 8.75e-14: 76.4: 11.36
+	Hs
		983379 DYN1_HUMAN (5-820): 0: 996: 62.07		ITSN1_HUMAN (66-488): 3e-12: 71.4: 9.37
+	Mm
		760488 DYN2_MOUSE (5-830): 0: 986: 63.59		ITSN1_MOUSE (48-488): 2.77e-15: 81: 12.30