HitPredict

Interactor 1: DYN1 (P39055)
Dynamin (EC 3.6.5.5)
Gene: dyn-1

Interactor 2: Q6AHQ8 (Q6AHQ8)
SH3 domain-containing protein
Gene: sdpn-1

Species: Caenorhabditis elegans

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.621

Property	Details
Experiments	23549480
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	PH~SH3_1
Common GO terms	GO:0005737 - cytoplasm GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 830 Ce			1 495
+	Ce
		760496 DYN1_CAEEL (1-762): 0: 986: 100.00		Q09989_CAEEL (7-495): 7.93e-91: 287: 100.00
+	Hs
		983417 DYN1_HUMAN (5-820): 0: 996: 62.07		PACN2_HUMAN (6-492): 7.21e-87: 277: 29.92
+	Mm
		760487 DYN2_MOUSE (5-830): 0: 986: 63.59		PACN2_MOUSE (6-492): 8.83e-90: 284: 29.51
+	Mm
		1142989 DYN3_MOUSE (5-830): 0: 1001: 63.76		PACN1_MOUSE (7-491): 3.2e-77: 250: 27.78
+	Hs
		983406 DYN1_HUMAN (5-820): 0: 996: 62.07		PACN1_HUMAN (6-491): 2.48e-78: 253: 27.72
+	Mm
		760451 DYN1_MOUSE (5-826): 0: 995: 62.05		PACN1_MOUSE (7-491): 3.2e-77: 250: 27.78
+	Rn
		599414 DYN1_RAT (5-820): 0: 991: 62.31		PACN1_RAT (7-491): 1.49e-77: 251: 28.19
+	Rn
		996551 DYN3_RAT (5-830): 0: 988: 62.66		PACN1_RAT (7-491): 1.49e-77: 251: 28.19
+	Mm
		760475 DYN2_MOUSE (5-830): 0: 986: 63.59		PACN1_MOUSE (7-491): 3.2e-77: 250: 27.78
+	Hs
		983416 DYN1_HUMAN (5-820): 0: 996: 62.07		PACN3_HUMAN (8-491): 1.03e-61: 209: 23.71
+	Mm
		760485 DYN2_MOUSE (5-830): 0: 986: 63.59		PACN3_MOUSE (8-491): 3.79e-63: 213: 24.54
+	Hs
		983392 DYN1_HUMAN (5-820): 0: 996: 62.07		NOSTN_HUMAN (22-495): 2.99e-51: 183: 15.20
+	Hs
		207784 DYN2_HUMAN (5-830): 0: 982: 63.05		PPIP1_HUMAN (7-491): 9.94e-50: 177: 14.49
+	Hs
		983372 DYN1_HUMAN (5-820): 0: 996: 62.07		MYO1E_HUMAN (1-491): 1.06e-40: 158: 12.55
+	Hs
		983403 DYN1_HUMAN (5-820): 0: 996: 62.07		FNBP1_HUMAN (20-433): 1.24e-39: 153: 13.27
+	Hs
		1301542 DYN3_HUMAN (5-830): 0: 987: 62.43		FNBP1_HUMAN (20-433): 1.24e-39: 153: 13.27
+	Mm
		760469 DYN1_MOUSE (5-826): 0: 995: 62.05		ITSN1_MOUSE (393-493): 1.06e-14: 79.5: 27.72
+	Hs
		983379 DYN1_HUMAN (5-820): 0: 996: 62.07		ITSN1_HUMAN (25-494): 9e-14: 76.4: 9.80
+	Rn
		599413 DYN1_RAT (5-820): 0: 991: 62.31		ITSN1_RAT (54-494): 9.67e-15: 79.4: 10.93
+	Mm
		760488 DYN2_MOUSE (5-830): 0: 986: 63.59		ITSN1_MOUSE (393-493): 1.06e-14: 79.5: 27.72