HitPredict

Interactor 1: SPT7 (P35177)
SAGA complex subunit SPT7 (Suppressor of Ty protein 7) (Transcriptional activator SPT7)
Gene: SPT7

Interactor 2: PRS4 (P40327)
26S proteasome regulatory subunit 4 homolog (Tat-binding homolog 5)
Gene: RPT2

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.63	1.00	0.799

Property	Details
Experiments	21734642, 24136112
Identification Methods	affinity chromatography technology, pull down, tandem affinity purification
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	AAA~Bromodomain
Common GO terms	GO:0005634 - nucleus
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 1332 Sc			1 437
+	Sc
		750817 SPT7_YEAST (1-1332): 0: 1180: 100.00		PRS6B_YEAST (57-419): 9.37e-112: 337: 48.77
+	Sc
		763006 SPT7_YEAST (1-1332): 0: 1180: 100.00		PRS8_YEAST (106-429): 1.25e-104: 318: 49.38
+	Hs
		969009 CBP_HUMAN (330-549): 8.67e-40: 164: 18.94		PRS8_HUMAN (38-432): 1.12e-122: 364: 42.42
+	Sc
		822429 GCN5_YEAST (435-548): 5.78e-20: 96.4: 29.83		PRS4_YEAST (1-437): 5.43e-133: 391: 100.00
+	Sc
		750886 GCN5_YEAST (435-548): 5.78e-20: 96.4: 29.83		PRS6B_YEAST (57-419): 9.37e-112: 337: 48.77
+	Sc
		1033876 GCN5_YEAST (435-548): 5.78e-20: 96.4: 29.83		PRS8_YEAST (106-429): 1.25e-104: 318: 49.38