HitPredict

Interactor 1: B4DUB1 (B4DUB1)
cyclin-dependent kinase (EC 2.7.11.22)
Gene: B4DUB1

Interactor 2: BIRC8 (Q96P09)
Baculoviral IAP repeat-containing protein 8 (Inhibitor of apoptosis-like protein 2) (IAP-like protein 2) (ILP-2) (Testis-specific inhibitor of apoptosis)
Gene: BIRC8

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.80	0.514

Property	Details
Experiments	28514442
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	BIR~Pkinase
Common GO terms	-
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 378 Hs			1 236
+	Hs
		1399323 CDK19_HUMAN (3-378): 1.04e-110: 334: 94.15		BIRC8_HUMAN (1-236): 1.71e-86: 257: 100.00
+	Hs
		691807 MK03_HUMAN (2-258): 2.88e-89: 275: 30.89		RFFL_HUMAN (64-236): 5.99e-24: 100: 17.78
+	Hs
		703668 MK01_HUMAN (2-256): 1.81e-89: 275: 28.79		RFFL_HUMAN (64-236): 5.99e-24: 100: 17.78
+	Hs
		188639 CDK1_HUMAN (3-214): 3.28e-86: 265: 33.49		BIRC5_HUMAN (4-100): 4.57e-27: 103: 27.89
+	Hs
		188645 CDK2_HUMAN (1-217): 4.17e-86: 264: 34.10		BIRC5_HUMAN (4-100): 4.57e-27: 103: 27.89
+	Hs
		443349 CDK1_HUMAN (3-214): 3.28e-86: 265: 33.49		BIRC3_HUMAN (4-158): 6.1e-18: 84.3: 24.20
+	Hs
		667828 CDK2_HUMAN (1-217): 4.17e-86: 264: 34.10		BIRC3_HUMAN (4-158): 6.1e-18: 84.3: 24.20
+	Hs
		443305 CDK1_HUMAN (3-214): 3.28e-86: 265: 33.49		XIAP_HUMAN (3-211): 1.27e-13: 71.6: 15.07