Protein: CDK19
Cyclin-dependent kinase 19 (EC 2.7.11.22) (CDC2-related protein kinase 6) (Cell division cycle 2-like protein kinase 6) (Cell division protein kinase 19) (Cyclin-dependent kinase 11) (Death-preventing kinase)

Gene: CDK19
Organism: Homo sapiens
Interactions: 81
UniProt ID: Q9BWU1

Gene Ontology (top 5):
GO:0004674 - protein serine/threonine kinase activity
GO:0004693 - cyclin-dependent protein serine/threonine kinase activity
GO:0005524 - ATP binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

666903

CCNC
Cyclin-C

10

20

Small-scale

0.972

High

239614

MED14
Mediator of RNA polymerase II transcription subunit 14

7

17

High-throughput

0.966

High

1416409

MED13
Mediator of RNA polymerase II transcription subunit 13

7

7

Small-scale

0.962

High

287816

MED6
Mediator of RNA polymerase II transcription subunit 6

6

4

High-throughput

0.947

High

1259068

MD13L
Mediator of RNA polymerase II transcription subunit 13-like

6

7

High-throughput

0.947

High

881600

CDK8
Cyclin-dependent kinase 8

5

18

Small-scale

0.915

High

1399323

BIRC8
Baculoviral IAP repeat-containing protein 8

2

9

High-throughput

0.789

High

1372189

MED12
Mediator of RNA polymerase II transcription subunit 12

11

12

Small-scale

0.756

High

49011

MED19
Mediator of RNA polymerase II transcription subunit 19

9

3

Small-scale

0.753

High

1416406

MED9
Mediator of RNA polymerase II transcription subunit 9

8

2

High-throughput

0.752

High

1416403

MED4
Mediator of RNA polymerase II transcription subunit 4

8

3

High-throughput

0.750

High

1416413

MED31
Mediator of RNA polymerase II transcription subunit 31

7

5

High-throughput

0.750

High

1416401

MED28
Mediator of RNA polymerase II transcription subunit 28

8

2

High-throughput

0.749

High

1416405

MED17
Mediator of RNA polymerase II transcription subunit 17

8

4

Small-scale

0.748

High

1416407

MED29
Mediator of RNA polymerase II transcription subunit 29

7

3

High-throughput

0.748

High

1151292

MED1
Mediator of RNA polymerase II transcription subunit 1

7

9

High-throughput

0.746

High

219513

MED7
Mediator of RNA polymerase II transcription subunit 7

6

5

High-throughput

0.736

High

282416

MED24
Mediator of RNA polymerase II transcription subunit 24

6

3

High-throughput

0.733

High

1149709

MED22
Mediator of RNA polymerase II transcription subunit 22

6

3

High-throughput

0.733

High

1241411

MED27
Mediator of RNA polymerase II transcription subunit 27

6

3

High-throughput

0.733

High

1391334

MED8
Mediator of RNA polymerase II transcription subunit 8

6

3

High-throughput

0.733

High

1401565

MED15
Mediator of RNA polymerase II transcription subunit 15

6

13

Small-scale

0.733

High

1416402

MED20
Mediator of RNA polymerase II transcription subunit 20

6

3

High-throughput

0.733

High

1416411

MED23
Mediator of RNA polymerase II transcription subunit 23

6

3

High-throughput

0.733

High

1416412

MED16
Mediator of RNA polymerase II transcription subunit 16

6

3

High-throughput

0.733

High

1108394

MED21
Mediator of RNA polymerase II transcription subunit 21

6

3

High-throughput

0.730

High

1413627

MED10
Mediator of RNA polymerase II transcription subunit 10

6

4

High-throughput

0.729

High

1160061

SRSF7
Serine/arginine-rich splicing factor 7

1

15

Small-scale

0.724

High

1393376

MED30
Mediator of RNA polymerase II transcription subunit 30

5

3

High-throughput

0.718

High

1416408

MED11
Mediator of RNA polymerase II transcription subunit 11

4

2

High-throughput

0.699

High

1414139

MED18
Mediator of RNA polymerase II transcription subunit 18

4

3

High-throughput

0.694

High

853732

MK08
Mitogen-activated protein kinase 8

1

20

High-throughput

0.691

High

1158514

CDC37
Hsp90 co-chaperone Cdc37

1

9

High-throughput

0.691

High

336028

MED26
Mediator of RNA polymerase II transcription subunit 26

4

1

Small-scale

0.691

High

832793

BCL6
B-cell lymphoma 6 protein

1

1

Small-scale

0.680

High

1295674

MD12L
Mediator of RNA polymerase II transcription subunit 12-like protein

5

14

High-throughput

0.652

High

897385

CDK7
Cyclin-dependent kinase 7

1

17

Small-scale

0.647

High

1259278

MED25
Mediator of RNA polymerase II transcription subunit 25

2

3

High-throughput

0.628

High

1416410

DJC12
DnaJ homolog subfamily C member 12

1

4

High-throughput

0.618

High

976144

RPB7
DNA-directed RNA polymerase II subunit RPB7

1

2

High-throughput

0.618

High

1144305

STK38
Serine/threonine-protein kinase 38

1

16

Small-scale

0.618

High

1366420

RT31
Small ribosomal subunit protein mS31

3

1

High-throughput

0.599

High

1416404

CYRIB
CYFIP-related Rac1 interactor B

3

1

High-throughput

0.599

High

897962

CDK9
Cyclin-dependent kinase 9

1

18

Small-scale

0.575

High

1307193

RB6I2
ELKS/Rab6-interacting/CAST family member 1

2

19

High-throughput

0.574

High

162682

ANM5
Protein arginine N-methyltransferase 5

1

5

Small-scale

0.561

High

1410360

MEP50
Methylosome protein WDR77

1

13

Small-scale

0.561

High

665940

IBP6
Insulin-like growth factor-binding protein 6

2

1

High-throughput

0.558

High

1388075

MTBP
Mdm2-binding protein

2

1

Small-scale

0.558

High

423840

APOD
Apolipoprotein D

1

2

High-throughput

0.536

High

533749

CLUS
Clusterin

1

1

High-throughput

0.536

High

669994

MCM3
DNA replication licensing factor MCM3

1

18

High-throughput

0.536

High

671850

ZA2G
Zinc-alpha-2-glycoprotein

1

6

High-throughput

0.536

High

755782

MCM4
DNA replication licensing factor MCM4

1

13

High-throughput

0.536

High

888304

MCM2
DNA replication licensing factor MCM2

1

17

High-throughput

0.536

High

1137258

CND1
Condensin complex subunit 1

1

2

High-throughput

0.536

High

1243771

FXL19
F-box/LRR-repeat protein 19

1

7

High-throughput

0.536

High

1336286

LS14A
Protein LSM14 homolog A

1

8

High-throughput

0.536

High

1383456

PBIP1
Pre-B-cell leukemia transcription factor-interacting protein 1

1

13

High-throughput

0.536

High

903471

SMCA4
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4

1

5

Small-scale

0.527

High

1137501

SUZ12
Polycomb protein SUZ12

1

1

Small-scale

0.527

High

1351962

RBCC1
RB1-inducible coiled-coil protein 1

1

20

High-throughput

0.515

High

553057

PIP
Prolactin-inducible protein

1

0

High-throughput

0.513

High

621735

RPB3
DNA-directed RNA polymerase II subunit RPB3

1

3

High-throughput

0.479

High

621955

RPAB1
DNA-directed RNA polymerases I, II, and III subunit RPABC1

1

1

High-throughput

0.479

High

667432

RPB1
DNA-directed RNA polymerase II subunit RPB1

1

12

High-throughput

0.479

High

723073

RPB2
DNA-directed RNA polymerase II subunit RPB2

1

5

High-throughput

0.479

High

787781

RPB9
DNA-directed RNA polymerase II subunit RPB9

1

5

High-throughput

0.479

High

877466

MASP1
Mannan-binding lectin serine protease 1

1

2

High-throughput

0.479

High

912117

RPAB3
DNA-directed RNA polymerases I, II, and III subunit RPABC3

1

1

High-throughput

0.479

High

1089005

TP53B
TP53-binding protein 1

1

8

High-throughput

0.479

High

1212027

ZC3HD
Zinc finger CCCH domain-containing protein 13

1

19

High-throughput

0.479

High

1257817

ACD11
Acyl-CoA dehydrogenase family member 11

1

3

High-throughput

0.479

High

1313042

RPAP2
Putative RNA polymerase II subunit B1 CTD phosphatase RPAP2

1

1

High-throughput

0.479

High

1367179

ESR2
Estrogen receptor beta

1

20

High-throughput

0.479

High

1416415

SCC4
MAU2 chromatid cohesion factor homolog

1

0

High-throughput

0.458

High

1380135

FBXW7
F-box/WD repeat-containing protein 7

1

12

High-throughput

0.445

High

1362063

LZIC
Protein LZIC

1

2

High-throughput

0.437

High

1309973

CC117
Coiled-coil domain-containing protein 117

1

0

High-throughput

0.426

High

1416414

TSSC4
U5 small nuclear ribonucleoprotein TSSC4

1

0

High-throughput

0.426

High

1349256

MYBPP
MYCBP-associated protein

1

0

High-throughput

0.269

Low


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Last updated: 11Aug2025