HitPredict

Interactor 1: IF4F2 (P39936)
Eukaryotic initiation factor 4F subunit p130 (eIF-4F p130) (eIF4F p130) (Translation initiation factor 4(4)-F(6) subunit gamma(3) protein 2) (eIF4G2) (mRNA cap-binding protein complex subunit p130)
Gene: TIF4632

Interactor 2: NAM8 (Q00539)
Protein NAM8 (Nuclear accommodation of mitochondria protein 8) (U1 snRNP component NAM8)
Gene: NAM8

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.73	0.60	0.662

Property	Details
Experiments	11805826, 16429126, 21558325
Identification Methods	tandem affinity purification, affinity chromatography technology
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003729 - mRNA binding
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 914 Sc			1 523
+	Sc
		376797 IF4F2_YEAST (1-914): 0: 614: 100.00		PABP_YEAST (3-323): 4.49e-41: 157: 12.87
+	Sc
		765032 IF4F1_YEAST (1-914): 1.37e-142: 449: 47.13		NAM8_YEAST (1-523): 7.39e-89: 284: 100.00
+	Sc
		376796 IF4F1_YEAST (1-914): 1.37e-142: 449: 47.13		PABP_YEAST (3-323): 4.49e-41: 157: 12.87
+	Hs
		979889 IF4G1_HUMAN (19-906): 2.59e-119: 399: 16.78		PABP4_HUMAN (2-328): 3.82e-46: 172: 11.11
+	Hs
		516476 IF4G1_HUMAN (19-906): 2.59e-119: 399: 16.78		PABP1_HUMAN (153-523): 6.99e-36: 143: 13.78
+	Hs
		203335 IF4G3_HUMAN (2-868): 6.9e-109: 370: 17.54		PABP1_HUMAN (153-523): 6.99e-36: 143: 13.78
+	Hs
		1031455 PAIP1_HUMAN (453-811): 8.3e-55: 199: 16.22		PABP4_HUMAN (2-328): 3.82e-46: 172: 11.11
+	Hs
		1119144 PAIP1_HUMAN (453-811): 8.3e-55: 199: 16.22		PAP1L_HUMAN (3-317): 1.64e-44: 167: 13.00
+	Mm
		665767 PAIP1_MOUSE (494-811): 8.43e-61: 214: 16.11		PABP1_MOUSE (153-523): 8.37e-36: 143: 13.78
+	Hs
		516685 PAIP1_HUMAN (453-811): 8.3e-55: 199: 16.22		PABP1_HUMAN (153-523): 6.99e-36: 143: 13.78
+	Hs
		998651 EP300_HUMAN (8-465): 2.15e-38: 158: 10.92		PABP4_HUMAN (2-328): 3.82e-46: 172: 11.11
+	Hs
		963553 CBP_HUMAN (10-391): 2.53e-50: 195: 14.15		TIAR_HUMAN (3-312): 6.51e-29: 119: 14.60
+	Hs
		516480 EP300_HUMAN (8-465): 2.15e-38: 158: 10.92		PABP1_HUMAN (153-523): 6.99e-36: 143: 13.78
+	Hs
		1020328 PAIP1_HUMAN (453-811): 8.3e-55: 199: 16.22		ELAV2_HUMAN (160-461): 1.51e-12: 70.8: 12.58
+	Hs
		516595 KMT2C_HUMAN (9-529): 1.98e-11: 70.6: 8.05		PABP1_HUMAN (153-523): 6.99e-36: 143: 13.78