Interactor 1: RSP5 (P39940)
E3 ubiquitin-protein ligase RSP5 (EC 2.3.2.26) (HECT-type E3 ubiquitin transferase RSP5) (Reverses SPT-phenotype protein 5)
Gene: RSP5

Interactor 2: BUL1 (P48524)
Ubiquitin ligase-binding protein BUL1 (Respiration deficiency suppressor 1)
Gene: BUL1

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.96 0.60 0.763

The method score is based on:

Property Details
Experiments 8668140, 11805837, 25998383, 9931424, 16554755, 18719252, 15713680, 15933713, 26508657, 17551511, 17645729, 20489023, 22307975
Identification Methods two hybrid, coimmunoprecipitation, anti tag coimmunoprecipitation, affinity chromatography technology, pull down, enzymatic study, tandem affinity purification
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000151 - ubiquitin ligase complex
GO:0005737 - cytoplasm
GO:0043162 - ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway
GO:0070086 - ubiquitin-dependent endocytosis
GO:1990306 - RSP5-BUL ubiquitin ligase complex
and 1 others

more...

Homologous interactions 3

Homologous interactions

Color coding for hit scores

1 809
Sc

1 976
+ Sc
+ Sc
+ Sc

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Last updated: 15 Jul 2024