HitPredict

Interactor 1: CEF1 (P39964)
Pre-mRNA-splicing factor cdc5 (Cell division control protein 5)
Gene: cdc5

Interactor 2: SF3B1 (Q10178)
U2 snRNP component prp10
Gene: prp10

Species: Schizosaccharomyces pombe 972h-

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.64	0.60	0.624

Property	Details
Experiments	15755920, 24014766, 11884590
Identification Methods	affinity chromatography technology, biochemical, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0045292 - mRNA cis splicing, via spliceosome GO:0071014 - post-mRNA release spliceosomal complex
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 757 Sp			1 1205
+	Hs
		268834 CDC5L_HUMAN (2-753): 3.79e-179: 534: 37.01		SF3B1_HUMAN (152-1205): 0: 1047: 59.24
+	Sc
		836931 CEF1_YEAST (2-581): 4.25e-88: 290: 29.10		SF3B1_YEAST (270-1201): 0: 781: 48.28
+	Hs
		1268230 CDC5L_HUMAN (2-753): 3.79e-179: 534: 37.01		GCN1_HUMAN (403-1197): 3.61e-31: 135: 14.04
+	Hs
		1273206 CDC5L_HUMAN (2-753): 3.79e-179: 534: 37.01		TNPO1_HUMAN (774-1190): 1.77e-20: 100: 10.02
+	Hs
		672255 CDC5L_HUMAN (2-753): 3.79e-179: 534: 37.01		2AAA_HUMAN (360-776): 2.76e-11: 70: 12.99