HitPredict

Interactor 1: NUG1 (P40010)
Nuclear GTP-binding protein NUG1 (Nuclear GTPase 1)
Gene: NUG1

Interactor 2: IF6 (Q12522)
Eukaryotic translation initiation factor 6 (eIF-6)
Gene: TIF6

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.78	0.60	0.686

Property	Details
Experiments	11779510, 16429126, 16095611, 37968396
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000463 - maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) GO:0005634 - nucleus GO:0005730 - nucleolus GO:0030687 - preribosome, large subunit precursor
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 520 Sc			1 245
+	Hs
		881038 GNL3L_HUMAN (14-520): 2.61e-116: 356: 24.44		IF6_HUMAN (1-245): 3.67e-144: 404: 72.25
+	Hs
		880918 NOG2_HUMAN (5-519): 4.99e-113: 353: 22.43		IF6_HUMAN (1-245): 3.67e-144: 404: 72.25
+	Sc
		864711 NOG2_YEAST (6-454): 1.32e-114: 349: 22.74		IF6_YEAST (1-245): 3.82e-140: 394: 100.00
+	Sc
		859651 LSG1_YEAST (58-509): 1.02e-94: 302: 17.13		IF6_YEAST (1-245): 3.82e-140: 394: 100.00
+	Hs
		881020 LSG1_HUMAN (15-242): 2.58e-60: 212: 14.96		IF6_HUMAN (1-245): 3.67e-144: 404: 72.25