HitPredict

Interactor 1: RSMB (P40018)
Small nuclear ribonucleoprotein-associated protein B (snRNP-B) (Sm protein B) (Sm-B) (SmB)
Gene: SMB1

Interactor 2: LSM8 (P47093)
U6 snRNA-associated Sm-like protein LSm8
Gene: LSM8

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.77	1.00	0.881

Property	Details
Experiments	11805837, 37968396, 21558325, 16429126
Identification Methods	anti tag coimmunoprecipitation, affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	LSM~LSM
Common GO terms	GO:0000398 - mRNA splicing, via spliceosome GO:0005634 - nucleus GO:0005681 - spliceosomal complex GO:0005737 - cytoplasm GO:0046540 - U4/U6 x U5 tri-snRNP complex and 1 others more... GO:0071001 - U4/U6 snRNP
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 196 Sc			1 109
+	Sc
		766911 RSMB_YEAST (1-196): 2.05e-94: 274: 100.00		RUXG_YEAST (2-69): 1.63e-17: 72.4: 21.62
+	Sc
		766934 RSMB_YEAST (1-196): 2.05e-94: 274: 100.00		LSM7_YEAST (5-71): 3.29e-13: 62.3: 15.00
+	Sc
		766937 RSMB_YEAST (1-196): 2.05e-94: 274: 100.00		LSM3_YEAST (5-76): 5.4e-10: 53.5: 22.22
+	Hs
		321370 RSMB_HUMAN (4-104): 8.53e-43: 145: 41.58		LSM8_HUMAN (1-85): 1.33e-29: 103: 27.47
+	Hs
		321392 RSMN_HUMAN (4-104): 4.51e-43: 145: 41.58		LSM8_HUMAN (1-85): 1.33e-29: 103: 27.47
+	Hs
		167663 RSMB_HUMAN (4-104): 8.53e-43: 145: 41.58		LSM1_HUMAN (2-102): 1.21e-28: 102: 21.70
+	Hs
		538891 RSMB_HUMAN (4-104): 8.53e-43: 145: 41.58		RUXG_HUMAN (3-69): 6.78e-25: 90.8: 20.29
+	Hs
		912026 RSMN_HUMAN (4-104): 4.51e-43: 145: 41.58		RUXG_HUMAN (3-69): 6.78e-25: 90.8: 20.29
+	Hs
		68400 RSMB_HUMAN (4-104): 8.53e-43: 145: 41.58		RUXGL_HUMAN (3-69): 6.48e-23: 85.8: 20.29
+	Hs
		68412 RSMN_HUMAN (4-104): 4.51e-43: 145: 41.58		RUXGL_HUMAN (3-69): 6.48e-23: 85.8: 20.29
+	Hs
		539178 RSMB_HUMAN (4-104): 8.53e-43: 145: 41.58		LSM7_HUMAN (5-81): 4.87e-19: 77: 17.24
+	Hs
		538826 RSMB_HUMAN (4-104): 8.53e-43: 145: 41.58		RSMB_HUMAN (2-64): 9.82e-17: 74.3: 20.00
+	Hs
		538899 RSMN_HUMAN (4-104): 4.51e-43: 145: 41.58		RSMB_HUMAN (2-64): 9.82e-17: 74.3: 20.00
+	Dm
		984916 Q8IPZ7_DROME (11-104): 4.72e-25: 96: 24.47		RSMB_DROME (4-64): 2.82e-14: 67: 23.29