HitPredict

Interactor 1: IMB4 (P40069)
Importin subunit beta-4 (Importin-123) (Karyopherin subunit beta-4) (Karyopherin-123) (Ran-binding protein YRB4)
Gene: KAP123

Interactor 2: NUP42 (P49686)
Nucleoporin NUP42 (Nuclear pore protein NUP42)
Gene: NUP42

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.57	0.60	0.586

Property	Details
Experiments	11387327, 9368759
Identification Methods	affinity chromatography technology, two hybrid
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005643 - nuclear pore GO:0006607 - NLS-bearing protein import into nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1113 Sc			1 430
+	Hs
		127197 IPO5_HUMAN (7-1105): 0: 563: 18.50		NU214_HUMAN (2-398): 4.04e-35: 140: 19.51
+	Sc
		767656 IMB4_YEAST (1-1113): 2.41e-177: 551: 100.00		NU159_YEAST (4-382): 6.37e-20: 94.9: 25.07
+	Sc
		541885 IMB4_YEAST (1-1113): 2.41e-177: 551: 100.00		NSP1_YEAST (2-421): 1.81e-13: 74.5: 12.47
+	Sc
		767712 IMB4_YEAST (1-1113): 2.41e-177: 551: 100.00		NU100_YEAST (63-417): 3.02e-09: 61.4: 17.31
+	Sc
		767713 IMB4_YEAST (1-1113): 2.41e-177: 551: 100.00		NU116_YEAST (29-419): 5.64e-09: 60.3: 16.07
+	Sc
		687968 IMB3_YEAST (5-1065): 1.11e-110: 372: 17.51		NUP42_YEAST (1-430): 1.55e-62: 210: 100.00
+	Sc
		687969 IMB3_YEAST (5-1065): 1.11e-110: 372: 17.51		NU145_YEAST (35-416): 3.3e-37: 146: 16.75
+	Sc
		687954 IMB3_YEAST (5-1065): 1.11e-110: 372: 17.51		NU159_YEAST (4-382): 6.37e-20: 94.9: 25.07
+	Sc
		541851 IMB3_YEAST (5-1065): 1.11e-110: 372: 17.51		NSP1_YEAST (2-421): 1.81e-13: 74.5: 12.47
+	Sc
		687986 IMB3_YEAST (5-1065): 1.11e-110: 372: 17.51		NU100_YEAST (63-417): 3.02e-09: 61.4: 17.31
+	Sc
		687987 IMB3_YEAST (5-1065): 1.11e-110: 372: 17.51		NU116_YEAST (29-419): 5.64e-09: 60.3: 16.07
+	Hs
		727300 TNPO1_HUMAN (215-1056): 1.35e-74: 267: 12.02		NU214_HUMAN (2-398): 4.04e-35: 140: 19.51
+	Hs
		867108 CAND1_HUMAN (1-1112): 1.78e-93: 327: 11.03		SC24C_HUMAN (105-420): 1.11e-09: 62.6: 13.88
+	Hs
		858024 TNPO1_HUMAN (215-1056): 1.35e-74: 267: 12.02		NUP98_HUMAN (46-360): 1.85e-13: 74.9: 14.03
+	Hs
		155553 TNPO2_HUMAN (215-1056): 9.61e-71: 256: 12.73		NUP98_HUMAN (46-360): 1.85e-13: 74.9: 14.03
+	Hs
		727254 IMB1_HUMAN (336-1075): 4.67e-46: 181: 11.11		NU214_HUMAN (2-398): 4.04e-35: 140: 19.51
+	Xl
		1137359 Q5U4V0_XENLA (215-1056): 3.18e-70: 254: 12.37		NU153_XENLA (14-421): 2.25e-09: 61.8: 14.56
+	Hs
		857978 IMB1_HUMAN (336-1075): 4.67e-46: 181: 11.11		NUP98_HUMAN (46-360): 1.85e-13: 74.9: 14.03
+	Xl
		853820 IMB_XENLA (336-1075): 2.65e-46: 182: 11.11		Q6DCP4_XENLA (25-414): 2.12e-10: 64.5: 17.59
+	Sc
		541927 IMB1_YEAST (6-696): 1.11e-36: 151: 13.31		NSP1_YEAST (2-421): 1.81e-13: 74.5: 12.47