HitPredict

Interactor 1: SSB2 (P40150)
Ribosome-associated molecular chaperone SSB2 (EC 3.6.4.10) (Heat shock protein SSB2) (Hsp70 chaperone Ssb)
Gene: SSB2

Interactor 2: RPN11 (P43588)
Ubiquitin carboxyl-terminal hydrolase RPN11 (EC 3.4.19.12) (26S proteasome regulatory subunit RPN11) (Protein MPR1)
Gene: RPN11

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.80	0.60	0.695

Property	Details
Experiments	23332755, 16284124, 18757749, 20170199, 19536198
Identification Methods	biochemical, affinity chromatography technology, tandem affinity purification
Interaction Type	association, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 613 Sc			1 306
+	Sc
		511750 SSB1_YEAST (1-613): 0: 1118: 99.35		RPN11_YEAST (1-306): 4.59e-91: 274: 100.00
+	Sc
		769679 SSB2_YEAST (1-613): 0: 1122: 100.00		RPN8_YEAST (25-305): 6.68e-51: 172: 16.03
+	Sc
		513026 SSB1_YEAST (1-613): 0: 1118: 99.35		RPN8_YEAST (25-305): 6.68e-51: 172: 16.03
+	Sc
		769871 SSB2_YEAST (1-613): 0: 1122: 100.00		CSN5_YEAST (2-278): 1.75e-46: 163: 22.60
+	Sc
		513303 SSB1_YEAST (1-613): 0: 1118: 99.35		CSN5_YEAST (2-278): 1.75e-46: 163: 22.60
+	Hs
		130712 HSP7C_HUMAN (5-612): 0: 897: 60.00		PSDE_HUMAN (16-306): 2.53e-98: 293: 67.35
+	Hs
		564143 HSP76_HUMAN (3-612): 0: 898: 58.82		CSN5_HUMAN (14-292): 7.24e-75: 234: 30.74
+	Hs
		504512 HSP7C_HUMAN (5-612): 0: 897: 60.00		CSN5_HUMAN (14-292): 7.24e-75: 234: 30.74
+	Hs
		714039 HS71L_HUMAN (5-612): 0: 893: 59.51		CSN5_HUMAN (14-292): 7.24e-75: 234: 30.74
+	Hs
		124744 HSP7C_HUMAN (5-612): 0: 897: 60.00		EIF3F_HUMAN (3-305): 7.75e-56: 186: 14.24
+	Sc
		605362 HSP74_YEAST (9-611): 0: 680: 62.15		RPN11_YEAST (1-306): 4.59e-91: 274: 100.00
+	Sc
		450086 HSP73_YEAST (9-611): 0: 677: 60.66		RPN11_YEAST (1-306): 4.59e-91: 274: 100.00