HitPredict

Interactor 1: TCPZ (P40227)
T-complex protein 1 subunit zeta (TCP-1-zeta) (Acute morphine dependence-related protein 2) (CCT-zeta-1) (Chaperonin containing T-complex polypeptide 1 subunit 6A) (HTR3) (Tcp20)
Gene: CCT6A

Interactor 2: EZH2 (Q15910)
Histone-lysine N-methyltransferase EZH2 (EC 2.1.1.356) (ENX-1) (Enhancer of zeste homolog 2) (Lysine N-methyltransferase 6)
Gene: EZH2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.50	0.533

Property	Details
Experiments	27634302, 36517590
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 531 Hs			1 746
+	Hs
		1080275 TCPH_HUMAN (2-530): 0: 576: 27.93		EZH2_HUMAN (1-746): 0: 862: 100.00
+	Hs
		826679 TCPG_HUMAN (3-528): 0: 559: 27.96		EZH2_HUMAN (1-746): 0: 862: 100.00
+	Mm
		945919 TCPH_MOUSE (2-530): 0: 582: 27.75		Q6AXH7_MOUSE (1-746): 0: 832: 96.41
+	Hs
		821226 TCPE_HUMAN (3-528): 0: 548: 30.47		EZH2_HUMAN (1-746): 0: 862: 100.00
+	Mm
		945980 TCPZ_MOUSE (1-531): 0: 574: 96.80		Q6AXH7_MOUSE (1-746): 0: 832: 96.41
+	Hs
		1080176 TCPW_HUMAN (1-530): 0: 542: 85.85		EZH2_HUMAN (1-746): 0: 862: 100.00
+	Mm
		945989 TCPG_MOUSE (3-528): 0: 558: 28.14		Q6AXH7_MOUSE (1-746): 0: 832: 96.41
+	Sc
		755770 TCPZ_YEAST (3-530): 0: 579: 56.75		SET1_YEAST (205-733): 1.13e-84: 292: 16.01
+	Sc
		755775 TCPH_YEAST (2-528): 0: 543: 25.84		SET1_YEAST (205-733): 1.13e-84: 292: 16.01
+	Hs
		1296406 TCPH_HUMAN (2-530): 0: 576: 27.93		EHMT2_HUMAN (467-732): 1.91e-68: 247: 24.21
+	Hs
		1306682 TCPH_HUMAN (2-530): 0: 576: 27.93		SUV92_HUMAN (447-734): 5.41e-74: 247: 24.10
+	Hs
		771045 TCPZ_HUMAN (1-531): 0: 573: 100.00		SUV92_HUMAN (447-734): 5.41e-74: 247: 24.10
+	Hs
		203775 TCPH_HUMAN (2-530): 0: 576: 27.93		SUV91_HUMAN (354-731): 2.25e-71: 240: 19.90
+	Hs
		203636 TCPZ_HUMAN (1-531): 0: 573: 100.00		SUV91_HUMAN (354-731): 2.25e-71: 240: 19.90
+	Hs
		826825 TCPG_HUMAN (3-528): 0: 559: 27.96		EHMT2_HUMAN (467-732): 1.91e-68: 247: 24.21
+	Hs
		826887 TCPG_HUMAN (3-528): 0: 559: 27.96		SUV92_HUMAN (447-734): 5.41e-74: 247: 24.10
+	Hs
		203640 TCPG_HUMAN (3-528): 0: 559: 27.96		SUV91_HUMAN (354-731): 2.25e-71: 240: 19.90
+	Hs
		821409 TCPE_HUMAN (3-528): 0: 548: 30.47		SUV92_HUMAN (447-734): 5.41e-74: 247: 24.10
+	Hs
		203639 TCPE_HUMAN (3-528): 0: 548: 30.47		SUV91_HUMAN (354-731): 2.25e-71: 240: 19.90
+	Hs
		770796 TCPZ_HUMAN (1-531): 0: 573: 100.00		KMT2A_HUMAN (606-733): 6.89e-19: 94.4: 39.54