HitPredict

Interactor 1: TCPZ (P40227)
T-complex protein 1 subunit zeta (TCP-1-zeta) (Acute morphine dependence-related protein 2) (CCT-zeta-1) (Chaperonin containing T-complex polypeptide 1 subunit 6A) (HTR3) (Tcp20)
Gene: CCT6A

Interactor 2: DCAF8 (Q5TAQ9)
DDB1- and CUL4-associated factor 8 (WD repeat-containing protein 42A)
Gene: DCAF8

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 531 Hs			1 597
+	Hs
		1135834 TCPH_HUMAN (2-530): 0: 576: 27.93		DCAF8_HUMAN (1-597): 5.38e-132: 400: 100.00
+	Hs
		473605 TCPH_HUMAN (2-530): 0: 576: 27.93		DC8L2_HUMAN (1-597): 8.22e-110: 344: 65.56
+	Hs
		473592 TCPZ_HUMAN (1-531): 0: 573: 100.00		DC8L2_HUMAN (1-597): 8.22e-110: 344: 65.56
+	Hs
		1295340 TCPH_HUMAN (2-530): 0: 576: 27.93		DCAF5_HUMAN (153-542): 6e-79: 269: 22.72
+	Hs
		770984 TCPZ_HUMAN (1-531): 0: 573: 100.00		DCAF5_HUMAN (153-542): 6e-79: 269: 22.72
+	Hs
		770968 TCPZ_HUMAN (1-531): 0: 573: 100.00		FBXW7_HUMAN (312-594): 7.67e-52: 191: 12.28
+	Hs
		1234373 TCPH_HUMAN (2-530): 0: 576: 27.93		WDTC1_HUMAN (405-597): 4.23e-46: 174: 30.30
+	Hs
		770929 TCPZ_HUMAN (1-531): 0: 573: 100.00		WDTC1_HUMAN (405-597): 4.23e-46: 174: 30.30
+	Hs
		770974 TCPZ_HUMAN (1-531): 0: 573: 100.00		SNR40_HUMAN (83-358): 2.66e-47: 171: 14.69
+	Hs
		903467 TCPH_HUMAN (2-530): 0: 576: 27.93		WDR5_HUMAN (278-585): 2.83e-45: 165: 12.18
+	Hs
		770771 TCPZ_HUMAN (1-531): 0: 573: 100.00		WDR5_HUMAN (278-585): 2.83e-45: 165: 12.18
+	Hs
		1306645 TCPH_HUMAN (2-530): 0: 576: 27.93		TBL1Y_HUMAN (365-588): 9.84e-37: 145: 9.87
+	Hs
		771009 TCPZ_HUMAN (1-531): 0: 573: 100.00		TBL1Y_HUMAN (365-588): 9.84e-37: 145: 9.87
+	Hs
		1240450 TCPH_HUMAN (2-530): 0: 576: 27.93		POC1A_HUMAN (77-223): 9.74e-22: 99.6: 15.33
+	Hs
		770932 TCPZ_HUMAN (1-531): 0: 573: 100.00		POC1A_HUMAN (77-223): 9.74e-22: 99.6: 15.33
+	Hs
		1202777 TCPH_HUMAN (2-530): 0: 576: 27.93		WDR5B_HUMAN (466-589): 5.53e-21: 96.2: 15.20
+	Hs
		770916 TCPZ_HUMAN (1-531): 0: 573: 100.00		WDR5B_HUMAN (466-589): 5.53e-21: 96.2: 15.20
+	Hs
		1166712 TCPH_HUMAN (2-530): 0: 576: 27.93		WDR82_HUMAN (329-546): 8.72e-13: 71.4: 10.90
+	Hs
		770898 TCPZ_HUMAN (1-531): 0: 573: 100.00		WDR82_HUMAN (329-546): 8.72e-13: 71.4: 10.90
+	Hs
		1306704 TCPH_HUMAN (2-530): 0: 576: 27.93		NLE1_HUMAN (86-182): 4.74e-11: 67.2: 8.25