Interactor 1: PRS4 (P40327)
26S proteasome regulatory subunit 4 homolog (Tat-binding homolog 5)
Gene: RPT2

Interactor 2: RPN11 (P43588)
Ubiquitin carboxyl-terminal hydrolase RPN11 (EC 3.4.19.12) (26S proteasome regulatory subunit RPN11) (Protein MPR1)
Gene: RPN11

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.97 1.00 0.988

The method score is based on:

Property Details
Experiments 22037170, 11805826, 16554755, 16284124, 16338358, 22215586, 24038880, 16429126, 26182356, 28106073, 26929360, 37968396, 34161281, 27405762, 31601863, 15917626, 21321079, 21627799, 21658604, 22237024 and 3 others

more...

Identification Methods pull down, tandem affinity purification, affinity chromatography technology, biochemical
Interaction Type physical association, association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains JAB~Prot_ATP_ID_OB
Common GO terms GO:0000502 - proteasome complex
GO:0005634 - nucleus
GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 437
Sc

1 306
+ Dm
+ Dm
+ Hs
+ At
+ Dm
+ Dm
+ Hs
+ Hs
+ Hs
+ Sp
+ Hs
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+ Sc
+ Dm
+ Dm
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+ Hs
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+ Hs

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Last updated: 15 Jul 2024