Protein: TRI56
E3 ubiquitin-protein ligase TRIM56 (EC 2.3.2.27) (RING finger protein 109) (Tripartite motif-containing protein 56)

Gene: TRI56, TRIM56
Organism: Homo sapiens
Interactions: 146
UniProt ID: Q9BRZ2

Gene Ontology (top 5):
GO:0003723 - RNA binding
GO:0004842 - ubiquitin-protein transferase activity
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

970996

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

20

High-throughput

0.698

High

977066

CNBP
CCHC-type zinc finger nucleic acid binding protein

3

1

High-throughput

0.667

High

1292869

STING
Stimulator of interferon genes protein

3

5

Small-scale

0.640

High

242747

PRKN
E3 ubiquitin-protein ligase parkin

1

20

High-throughput

0.618

High

623509

RO52
E3 ubiquitin-protein ligase TRIM21

1

18

High-throughput

0.618

High

1255289

TRI67
Tripartite motif-containing protein 67

1

19

High-throughput

0.618

High

428946

RLA0
Large ribosomal subunit protein uL10

2

2

High-throughput

0.601

High

461877

HS90A
Heat shock protein HSP 90-alpha

2

17

High-throughput

0.584

High

396832

ESR1
Estrogen receptor

2

20

High-throughput

0.571

High

810329

RL3
Large ribosomal subunit protein uL3

2

3

High-throughput

0.571

High

191783

MAGB2
Melanoma-associated antigen B2

2

20

High-throughput

0.549

High

187170

PPM1G
Protein phosphatase 1G

1

3

High-throughput

0.536

High

287114

PRKRA
Interferon-inducible double-stranded RNA-dependent protein kinase activator A

1

20

High-throughput

0.536

High

521902

H14
Histone H1.4

1

9

High-throughput

0.536

High

686382

RL13
Large ribosomal subunit protein eL13

1

3

High-throughput

0.536

High

772988

MYH9
Myosin-9

1

11

High-throughput

0.536

High

785407

RL4
Large ribosomal subunit protein uL4

1

3

High-throughput

0.536

High

824322

RL13A
Large ribosomal subunit protein uL13

1

2

High-throughput

0.536

High

898791

RL14
Large ribosomal subunit protein eL14

1

2

High-throughput

0.536

High

975904

RL7A
Large ribosomal subunit protein eL8

1

3

High-throughput

0.536

High

985850

RL11
Large ribosomal subunit protein uL5

1

2

High-throughput

0.536

High

1099508

SRSF6
Serine/arginine-rich splicing factor 6

1

17

High-throughput

0.536

High

1258265

UBP43
Ubiquitin carboxyl-terminal hydrolase 43

1

20

High-throughput

0.536

High

1412103

ZN346
Zinc finger protein 346

1

2

High-throughput

0.536

High

1412106

ING4
Inhibitor of growth protein 4

1

1

High-throughput

0.536

High

1307144

TCAM1
TIR domain-containing adapter molecule 1

1

3

Small-scale

0.515

High

1334219

SPC24
Kinetochore protein Spc24

1

0

High-throughput

0.513

High

1361746

DGCR8
Microprocessor complex subunit DGCR8

1

0

High-throughput

0.513

High

1412111

RL36
Large ribosomal subunit protein eL36

1

0

High-throughput

0.513

High

134849

SAP18
Histone deacetylase complex subunit SAP18

1

1

Small-scale

0.479

High

194320

R113A
E3 ubiquitin-protein ligase RNF113A

1

2

High-throughput

0.479

High

214014

M3K7
Mitogen-activated protein kinase kinase kinase 7

1

11

Small-scale

0.479

High

259075

DNJA2
DnaJ homolog subfamily A member 2

1

9

High-throughput

0.479

High

260381

BRD4
Bromodomain-containing protein 4

1

16

Small-scale

0.479

High

270736

N4BP1
NEDD4-binding protein 1

1

3

High-throughput

0.479

High

272424

OBSL1
Obscurin-like protein 1

1

4

High-throughput

0.479

High

346681

TTC4
Tetratricopeptide repeat protein 4

1

17

High-throughput

0.479

High

352534

TOP3B
DNA topoisomerase 3-beta-1

1

2

High-throughput

0.479

High

401396

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

18

High-throughput

0.479

High

468745

HS90B
Heat shock protein HSP 90-beta

1

19

High-throughput

0.479

High

474939

VIME
Vimentin

1

14

Small-scale

0.479

High

487691

PARP1
Poly [ADP-ribose] polymerase 1

1

14

High-throughput

0.479

High

688303

TTP
mRNA decay activator protein ZFP36

1

9

High-throughput

0.479

High

727944

DNJA1
DnaJ homolog subfamily A member 1

1

9

High-throughput

0.479

High

839815

EPS15
Epidermal growth factor receptor substrate 15

1

12

High-throughput

0.479

High

872690

SOX2
Transcription factor SOX-2

1

18

High-throughput

0.479

High

875764

PRC2A
Protein PRRC2A

1

19

High-throughput

0.479

High

880109

AL9A1
4-trimethylaminobutyraldehyde dehydrogenase

1

2

High-throughput

0.479

High

900129

FXR1
RNA-binding protein FXR1

1

15

Small-scale

0.479

High

900484

FXR2
RNA-binding protein FXR2

1

15

High-throughput

0.479

High

1032404

OTUD4
OTU domain-containing protein 4

1

5

High-throughput

0.479

High

1035877

KIF23
Kinesin-like protein KIF23

1

20

High-throughput

0.479

High

1038688

FKBP4
Peptidyl-prolyl cis-trans isomerase FKBP4

1

9

High-throughput

0.479

High

1056937

FMR1
Fragile X messenger ribonucleoprotein 1

1

15

High-throughput

0.479

High

1061612

FOXM1
Forkhead box protein M1

1

7

Small-scale

0.479

High

1100994

G3BP1
Ras GTPase-activating protein-binding protein 1

1

5

High-throughput

0.479

High

1106054

FKBP5
Peptidyl-prolyl cis-trans isomerase FKBP5

1

9

High-throughput

0.479

High

1107469

BIRC2
Baculoviral IAP repeat-containing protein 2

1

16

Small-scale

0.479

High

1114143

CUL3
Cullin-3

1

20

High-throughput

0.479

High

1115964

DYR1A
Dual specificity tyrosine-phosphorylation-regulated kinase 1A

1

15

High-throughput

0.479

High

1122146

UBP2L
Ubiquitin-associated protein 2-like

1

17

High-throughput

0.479

High

1129493

PUM1
Pumilio homolog 1

1

9

High-throughput

0.479

High

1138945

R3HD1
R3H domain-containing protein 1

1

13

High-throughput

0.479

High

1140770

KIF14
Kinesin-like protein KIF14

1

20

High-throughput

0.479

High

1146792

PCBP1
Poly(rC)-binding protein 1

1

14

Small-scale

0.479

High

1161632

IF16
Gamma-interferon-inducible protein 16

1

8

High-throughput

0.479

High

1165495

CPEB4
Cytoplasmic polyadenylation element-binding protein 4

1

12

High-throughput

0.479

High

1227361

A16L1
Autophagy-related protein 16-1

1

19

High-throughput

0.479

High

1240486

DHX57
Putative ATP-dependent RNA helicase DHX57

1

20

High-throughput

0.479

High

1252375

MEX3B
RNA-binding protein MEX3B

1

2

High-throughput

0.479

High

1275643

ZCCHV
Zinc finger CCCH-type antiviral protein 1

1

15

High-throughput

0.479

High

1280728

YTHD3
YTH domain-containing family protein 3

1

9

High-throughput

0.479

High

1308581

NUDC3
NudC domain-containing protein 3

1

6

High-throughput

0.479

High

1310638

Z3H7A
Zinc finger CCCH domain-containing protein 7A

1

16

High-throughput

0.479

High

1324997

ASCC3
Activating signal cointegrator 1 complex subunit 3

1

20

High-throughput

0.479

High

1330918

CGAS
Cyclic GMP-AMP synthase

1

2

Small-scale

0.479

High

1331961

ASCC1
Activating signal cointegrator 1 complex subunit 1

1

5

High-throughput

0.479

High

1336285

LS14A
Protein LSM14 homolog A

1

7

High-throughput

0.479

High

1357541

DCAF4
DDB1- and CUL4-associated factor 4

1

1

High-throughput

0.479

High

1358101

NUDC2
NudC domain-containing protein 2

1

6

High-throughput

0.479

High

1367143

ESR2
Estrogen receptor beta

1

20

High-throughput

0.479

High

1370086

RENT1
Regulator of nonsense transcripts 1

1

8

High-throughput

0.479

High

1380123

FBXW7
F-box/WD repeat-containing protein 7

1

15

High-throughput

0.479

High

1393034

PDLI5
PDZ and LIM domain protein 5

1

19

Small-scale

0.479

High

1393935

FUBP3
Far upstream element-binding protein 3

1

20

High-throughput

0.479

High

1404730

RING2
E3 ubiquitin-protein ligase RING2

1

19

High-throughput

0.479

High

1406475

ATX2
Ataxin-2

1

9

High-throughput

0.479

High

1412091

MKRN2
E3 ubiquitin-protein ligase makorin-2

1

4

High-throughput

0.479

High

1412093

TDRD3
Tudor domain-containing protein 3

1

2

High-throughput

0.479

High

1412094

MOV10
Helicase MOV-10

1

8

High-throughput

0.479

High

1412096

CYLD
Ubiquitin carboxyl-terminal hydrolase CYLD

1

5

High-throughput

0.479

High

1412097

ANLN
Anillin

1

4

High-throughput

0.479

High

1412098

4ET
Eukaryotic translation initiation factor 4E transporter

1

1

High-throughput

0.479

High

1412100

ZCHC3
Zinc finger CCHC domain-containing protein 3

1

1

High-throughput

0.479

High

1412101

F120A
Constitutive coactivator of PPAR-gamma-like protein 1

1

4

High-throughput

0.479

High

1412102

ZRAN1
Ubiquitin thioesterase ZRANB1

1

19

High-throughput

0.479

High

1412104

BRPF3
Bromodomain and PHD finger-containing protein 3

1

11

High-throughput

0.479

High

1412108

R3HD2
R3H domain-containing protein 2

1

14

High-throughput

0.479

High

1412109

SGT1
Protein SGT1 homolog

1

11

High-throughput

0.479

High

1412113

PRC2C
Protein PRRC2C

1

18

High-throughput

0.479

High

1412114

YTHD2
YTH domain-containing family protein 2

1

10

High-throughput

0.479

High

1412115

IF2B2
Insulin-like growth factor 2 mRNA-binding protein 2

1

20

High-throughput

0.479

High

1144143

TEBP
Prostaglandin E synthase 3

1

0

High-throughput

0.458

High

1151380

TRIP4
Activating signal cointegrator 1

1

0

High-throughput

0.458

High

1383235

CLUA1
Clusterin-associated protein 1

1

0

High-throughput

0.458

High

1411690

RIOK1
Serine/threonine-protein kinase RIO1

1

0

High-throughput

0.458

High

1412092

ASCC2
Activating signal cointegrator 1 complex subunit 2

1

0

High-throughput

0.458

High

1412099

I17RB
Interleukin-17 receptor B

1

0

Small-scale

0.458

High

1412110

DOP1B
Protein DOP1B

1

0

High-throughput

0.458

High

1412112

MARF1
Meiosis regulator and mRNA stability factor 1

1

0

High-throughput

0.458

High

288750

NPM3
Nucleoplasmin-3

1

8

High-throughput

0.445

High

290703

SURF6
Surfeit locus protein 6

1

6

High-throughput

0.445

High

601839

HMGA1
High mobility group protein HMG-I/HMG-Y

1

1

High-throughput

0.445

High

765838

BMI1
Polycomb complex protein BMI-1

1

18

High-throughput

0.445

High

969400

RS8
Small ribosomal subunit protein eS8

1

3

High-throughput

0.445

High

1008865

RED1
Double-stranded RNA-specific editase 1

1

16

High-throughput

0.445

High

1037343

H11
Histone H1.1

1

9

High-throughput

0.445

High

1099225

SRSF5
Serine/arginine-rich splicing factor 5

1

17

High-throughput

0.445

High

1128100

DHX8
ATP-dependent RNA helicase DHX8

1

15

High-throughput

0.445

High

1140005

RRS1
Ribosome biogenesis regulatory protein homolog

1

2

High-throughput

0.445

High

1239925

CAVN1
Caveolae-associated protein 1

1

1

High-throughput

0.445

High

1244327

PSRC1
Proline/serine-rich coiled-coil protein 1

1

1

High-throughput

0.445

High

1326060

RYBP
RING1 and YY1-binding protein

1

3

High-throughput

0.445

High

1411882

UTP23
rRNA-processing protein UTP23 homolog

1

3

High-throughput

0.445

High

1412088

MMTA2
Multiple myeloma tumor-associated protein 2

1

3

High-throughput

0.445

High

1412090

REXO4
RNA exonuclease 4

1

5

High-throughput

0.445

High

1412105

ABT1
Activator of basal transcription 1

1

1

High-throughput

0.445

High

1412107

RL26L
Ribosomal protein uL24-like

1

3

High-throughput

0.445

High

76569

B4DYC6
cDNA FLJ60958, highly similar to Homo sapiens SGT1, suppressor of G2 allele of SKP1

1

4

High-throughput

0.437

High

175511

KHNYN
Protein KHNYN

1

3

High-throughput

0.437

High

611748

BMP7
Bone morphogenetic protein 7

1

4

Small-scale

0.437

High

1194082

MINY4
Probable ubiquitin carboxyl-terminal hydrolase MINDY-4

1

1

High-throughput

0.437

High

1245572

Q6PK50
HSP90AB1 protein

1

19

High-throughput

0.437

High

1256576

CE128
Centrosomal protein of 128 kDa

1

18

High-throughput

0.437

High

1383660

VP33A
Vacuolar protein sorting-associated protein 33A

1

6

High-throughput

0.437

High

1386340

FAF2
FAS-associated factor 2

1

8

Small-scale

0.437

High

1412087

GDAH
Guanidino acid hydrolase, mitochondrial

1

1

High-throughput

0.437

High

1412089

SYTM
Threonine--tRNA ligase, mitochondrial

1

2

High-throughput

0.437

High

1412095

ALG13
UDP-N-acetylglucosamine transferase subunit ALG13

1

9

High-throughput

0.437

High

208360

RRP8
Ribosomal RNA-processing protein 8

1

0

High-throughput

0.426

High

1136849

MO4L2
Mortality factor 4-like protein 2

1

0

High-throughput

0.426

High

1179361

TSR1
Pre-rRNA-processing protein TSR1 homolog

1

0

High-throughput

0.426

High

1411537

PYM1
Partner of Y14 and mago

1

0

High-throughput

0.426

High

1127476

FGFP1
Fibroblast growth factor-binding protein 1

1

0

High-throughput

0.279

Low

1392337

BORC6
BLOC-1-related complex subunit 6

1

0

High-throughput

0.249

Low

652671

GNLY
Granulysin

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025