HitPredict

Interactor 1: PRK1 (P40494)
Actin-regulating kinase PRK1 (EC 2.7.11.1) (p53-regulating kinase 1)
Gene: PRK1

Interactor 2: AP18B (P53309)
Clathrin coat assembly protein AP180B
Gene: YAP1802

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.50	0.570

Property	Details
Experiments	18719252, 20489023
Identification Methods	two hybrid, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 810 Sc			1 568
+	Sc
		756304 PRK1_YEAST (1-810): 1.43e-171: 517: 100.00		AP18A_YEAST (3-558): 4.03e-111: 346: 44.33
+	Sc
		861369 ARK1_YEAST (1-667): 8.18e-130: 403: 41.67		AP18B_YEAST (1-568): 8.21e-139: 416: 100.00
+	Sc
		704785 PRK1_YEAST (1-810): 1.43e-171: 517: 100.00		SLA2_YEAST (1-349): 3.36e-71: 247: 13.09
+	Sc
		756309 ARK1_YEAST (1-667): 8.18e-130: 403: 41.67		AP18A_YEAST (3-558): 4.03e-111: 346: 44.33
+	Hs
		1036490 BMP2K_HUMAN (13-378): 1.82e-94: 322: 31.15		PICAL_HUMAN (3-557): 9.13e-119: 367: 18.66
+	Mm
		949298 TNIK_MOUSE (2-783): 6.38e-117: 386: 14.09		AP180_MOUSE (3-499): 2.37e-91: 301: 19.96
+	Sc
		743873 AKL1_YEAST (1-576): 3.06e-100: 337: 31.58		AP18A_YEAST (3-558): 4.03e-111: 346: 44.33
+	Sc
		704796 ARK1_YEAST (1-667): 8.18e-130: 403: 41.67		SLA2_YEAST (1-349): 3.36e-71: 247: 13.09
+	Sc
		704775 AKL1_YEAST (1-576): 3.06e-100: 337: 31.58		SLA2_YEAST (1-349): 3.36e-71: 247: 13.09
+	Hs
		161653 GAK_HUMAN (12-298): 2.35e-38: 156: 34.24		PICAL_HUMAN (3-557): 9.13e-119: 367: 18.66
+	Hs
		161596 GAK_HUMAN (12-298): 2.35e-38: 156: 34.24		HIP1R_HUMAN (2-357): 2.37e-90: 302: 13.51
+	Hs
		124341 GAK_HUMAN (12-298): 2.35e-38: 156: 34.24		HIP1_HUMAN (4-364): 6.6e-89: 297: 13.79
+	Hs
		253762 BMP2K_HUMAN (13-378): 1.82e-94: 322: 31.15		AUXI_HUMAN (265-562): 5.33e-27: 118: 11.80
+	Hs
		161595 GAK_HUMAN (12-298): 2.35e-38: 156: 34.24		AUXI_HUMAN (265-562): 5.33e-27: 118: 11.80