Protein: XPO4
Exportin-4 (Exp4)

Gene: XPO4
Organism: Homo sapiens
Interactions: 103
UniProt ID: Q9C0E2

Gene Ontology (top 5):
GO:0005049 - nuclear export signal receptor activity
GO:0005634 - nucleus
GO:0005643 - nuclear pore
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1421113

TN13B
Tumor necrosis factor ligand superfamily member 13B

4

2

High-throughput

0.699

High

890590

RBP2
E3 SUMO-protein ligase RanBP2

1

5

High-throughput

0.691

High

291701

XRP2
Protein XRP2

3

2

High-throughput

0.667

High

1421106

PD1L1
Programmed cell death 1 ligand 1

3

14

High-throughput

0.667

High

1334408

UXS1
UDP-glucuronic acid decarboxylase 1

3

1

High-throughput

0.662

High

906169

AL3A2
Aldehyde dehydrogenase family 3 member A2

3

0

High-throughput

0.638

High

262299

SCN2B
Sodium channel regulatory subunit beta-2

4

16

High-throughput

0.630

High

1291677

CMTD1
Catechol O-methyltransferase domain-containing protein 1

4

4

High-throughput

0.630

High

1421109

FZD10
Frizzled-10

2

1

High-throughput

0.628

High

981686

RAN
GTP-binding nuclear protein Ran

1

6

Small-scale

0.618

High

658979

PTPRE
Receptor-type tyrosine-protein phosphatase epsilon

2

7

High-throughput

0.611

High

1356874

PTPM1
Phosphatidylglycerophosphatase and protein-tyrosine phosphatase 1

2

5

High-throughput

0.611

High

774607

BASI
Basigin

3

7

High-throughput

0.609

High

845478

PE2R3
Prostaglandin E2 receptor EP3 subtype

3

10

High-throughput

0.609

High

1394321

VSIG2
V-set and immunoglobulin domain-containing protein 2

3

9

High-throughput

0.609

High

1421100

P2Y12
P2Y purinoceptor 12

3

20

High-throughput

0.609

High

1421110

CAH14
Carbonic anhydrase 14

3

3

High-throughput

0.609

High

50685

HACL2
2-hydroxyacyl-CoA lyase 2

3

3

High-throughput

0.604

High

640282

EPHA1
Ephrin type-A receptor 1

3

2

High-throughput

0.604

High

1421102

PACC1
Proton-activated chloride channel

3

1

High-throughput

0.604

High

388290

GLPA
Glycophorin-A

2

4

High-throughput

0.601

High

1326222

PNKD
Probable thioesterase PNKD

2

0

High-throughput

0.585

High

363829

EGFR
Epidermal growth factor receptor

2

9

Small-scale

0.584

High

749272

CD70
CD70 antigen

2

2

High-throughput

0.574

High

770914

OPRM
Mu-type opioid receptor

2

15

High-throughput

0.574

High

835379

VIPR2
Vasoactive intestinal polypeptide receptor 2

2

6

High-throughput

0.574

High

1232130

VASN
Vasorin

2

3

High-throughput

0.574

High

1330741

SIGL1
SIGLEC family-like protein 1

2

1

High-throughput

0.574

High

1421104

LRRC4
Leucine-rich repeat-containing protein 4

2

2

High-throughput

0.574

High

683333

TNR5
Tumor necrosis factor receptor superfamily member 5

2

7

High-throughput

0.549

High

1101657

GPR17
Uracil nucleotide/cysteinyl leukotriene receptor

2

20

High-throughput

0.549

High

1421099

UN93B
Protein unc-93 homolog B1

2

4

High-throughput

0.549

High

1421105

OCAD1
OCIA domain-containing protein 1

2

2

High-throughput

0.549

High

1421108

CC018
Uncharacterized protein C3orf18

2

2

High-throughput

0.549

High

1421117

NPTN
Neuroplastin

2

8

High-throughput

0.549

High

210421

MTLR
Motilin receptor

1

16

High-throughput

0.536

High

486613

TACD2
Tumor-associated calcium signal transducer 2

1

1

High-throughput

0.536

High

564344

CFTR
Cystic fibrosis transmembrane conductance regulator

1

5

High-throughput

0.536

High

638240

S1PR1
Sphingosine 1-phosphate receptor 1

1

11

High-throughput

0.536

High

638517

FPR1
fMet-Leu-Phe receptor

1

20

High-throughput

0.536

High

854736

RAGP1
Ran GTPase-activating protein 1

1

6

High-throughput

0.536

High

993737

UBC9
SUMO-conjugating enzyme UBC9

1

2

High-throughput

0.536

High

1022952

EFNB1
Ephrin-B1

1

5

High-throughput

0.536

High

1421103

BRF2
Transcription factor IIIB 50 kDa subunit

1

3

High-throughput

0.515

High

1421115

PHLA3
Pleckstrin homology-like domain family A member 3

1

1

High-throughput

0.515

High

303697

JTB
Protein JTB

1

0

High-throughput

0.513

High

1257219

PKHM3
Pleckstrin homology domain-containing family M member 3

1

0

High-throughput

0.513

High

1310386

HSC20
Iron-sulfur cluster co-chaperone protein HscB

1

0

High-throughput

0.513

High

992645

IF5A1
Eukaryotic translation initiation factor 5A-1

1

1

Small-scale

0.501

High

71246

HIDE1
Protein HIDE1

1

1

High-throughput

0.489

High

209107

CYB5B
Cytochrome b5 type B

1

3

High-throughput

0.489

High

253895

TPST2
Protein-tyrosine sulfotransferase 2

1

1

High-throughput

0.489

High

466964

ACM4
Muscarinic acetylcholine receptor M4

1

4

High-throughput

0.489

High

640460

C5AR1
C5a anaphylatoxin chemotactic receptor 1

1

16

High-throughput

0.489

High

719836

V2R
Vasopressin V2 receptor

1

14

High-throughput

0.489

High

833865

P2RY2
P2Y purinoceptor 2

1

20

High-throughput

0.489

High

868016

GLR
Glucagon receptor

1

8

High-throughput

0.489

High

936118

PAR2
Proteinase-activated receptor 2

1

20

High-throughput

0.489

High

1055140

CCG1
Voltage-dependent calcium channel gamma-1 subunit

1

1

High-throughput

0.489

High

1142174

P2RY6
P2Y purinoceptor 6

1

20

High-throughput

0.489

High

1249844

BTNL9
Butyrophilin-like protein 9

1

4

High-throughput

0.489

High

1291887

P2RY8
S-geranylgeranyl-glutathione receptor P2RY8

1

20

High-throughput

0.489

High

1399604

OPALI
Opalin

1

3

High-throughput

0.489

High

1406543

KI2L4
Killer cell immunoglobulin-like receptor 2DL4

1

3

High-throughput

0.489

High

1421098

F234A
Protein FAM234A

1

3

High-throughput

0.489

High

1421112

GPR34
Probable G-protein coupled receptor 34

1

19

High-throughput

0.489

High

1421116

GPR45
Probable G-protein coupled receptor 45

1

11

High-throughput

0.489

High

1421111

UBQL1
Ubiquilin-1

1

1

High-throughput

0.481

High

839360

MTOR
Serine/threonine-protein kinase mTOR

1

4

High-throughput

0.479

High

941547

CTBP2
C-terminal-binding protein 2

1

2

High-throughput

0.479

High

1164080

PTPRN
Receptor-type tyrosine-protein phosphatase-like N

1

12

High-throughput

0.479

High

1255438

TRI67
Tripartite motif-containing protein 67

1

9

High-throughput

0.479

High

1276756

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

5

High-throughput

0.479

High

1415153

LST8
Target of rapamycin complex subunit LST8

1

13

High-throughput

0.479

High

1421101

PKHA4
Pleckstrin homology domain-containing family A member 4

1

17

High-throughput

0.479

High

1421107

ZRAN1
Ubiquitin thioesterase ZRANB1

1

13

High-throughput

0.479

High

1421114

GSTK1
Glutathione S-transferase kappa 1

1

2

High-throughput

0.479

High

166408

ZNT4
Probable proton-coupled zinc antiporter SLC30A4

1

4

High-throughput

0.445

High

171573

S27A2
Long-chain fatty acid transport protein 2

1

9

High-throughput

0.445

High

1227414

A16L1
Autophagy-related protein 16-1

1

16

High-throughput

0.445

High

1366216

LPAR1
Lysophosphatidic acid receptor 1

1

15

High-throughput

0.445

High

1404942

S1PR3
Sphingosine 1-phosphate receptor 3

1

11

High-throughput

0.445

High

412578

NTRK1
High affinity nerve growth factor receptor

1

6

High-throughput

0.437

High

614731

PTPRA
Receptor-type tyrosine-protein phosphatase alpha

1

7

High-throughput

0.437

High

895217

5HT6R
5-hydroxytryptamine receptor 6

1

3

Small-scale

0.437

High

1251555

THADA
tRNA

1

1

High-throughput

0.437

High

704071

5HT1E
5-hydroxytryptamine receptor 1E

1

4

High-throughput

0.407

High

732942

GASR
Gastrin/cholecystokinin type B receptor

1

5

High-throughput

0.407

High

1196215

S22A6
Solute carrier family 22 member 6

1

3

High-throughput

0.407

High

1231465

ATLA3
Atlastin-3

1

1

Small-scale

0.407

High

1240953

S27A4
Long-chain fatty acid transport protein 4

1

9

High-throughput

0.407

High

1243661

S27A1
Long-chain fatty acid transport protein 1

1

9

High-throughput

0.407

High

1293901

VSIG1
V-set and immunoglobulin domain-containing protein 1

1

9

High-throughput

0.407

High

1391460

S35A4
Probable UDP-sugar transporter protein SLC35A4

1

1

High-throughput

0.407

High

316561

B3GA3
Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 3

1

0

High-throughput

0.279

Low

322166

GLCE
D-glucuronyl C5-epimerase

1

0

High-throughput

0.279

Low

592741

LEUK
Leukosialin

1

0

High-throughput

0.279

Low

1238255

CK087
Uncharacterized protein C11orf87

1

0

High-throughput

0.279

Low

1420839

SEM4C
Semaphorin-4C

1

0

High-throughput

0.279

Low

1279081

RIC3
Protein RIC-3

1

0

High-throughput

0.232

Low

1289149

OSTA
Organic solute transporter subunit alpha

1

0

High-throughput

0.232

Low

1350790

MO2R1
Cell surface glycoprotein CD200 receptor 1

1

0

High-throughput

0.232

Low

1390784

S47A1
Multidrug and toxin extrusion protein 1

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025