Protein: XPO6
Exportin-6 (Exp6) (Ran-binding protein 20)

Gene: XPO6
Organism: Homo sapiens
Interactions: 85
UniProt ID: Q96QU8

Gene Ontology (top 5):
GO:0005049 - nuclear export signal receptor activity
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005730 - nucleolus
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

262290

SCN2B
Sodium channel regulatory subunit beta-2

4

3

High-throughput

0.691

High

789203

NUP62
Nuclear pore glycoprotein p62

4

0

High-throughput

0.678

High

1394320

VSIG2
V-set and immunoglobulin domain-containing protein 2

3

1

High-throughput

0.667

High

1401084

PD1L1
Programmed cell death 1 ligand 1

3

3

High-throughput

0.667

High

332696

LYPD3
Ly6/PLAUR domain-containing protein 3

3

0

High-throughput

0.638

High

1401087

CAH14
Carbonic anhydrase 14

3

0

High-throughput

0.638

High

1398941

ZMAT2
Zinc finger matrin-type protein 2

3

0

High-throughput

0.634

High

669053

FPR2
N-formyl peptide receptor 2

2

5

High-throughput

0.628

High

770905

OPRM
Mu-type opioid receptor

2

3

High-throughput

0.628

High

1228646

NR3L1
Natural cytotoxicity triggering receptor 3 ligand 1

2

2

High-throughput

0.628

High

466953

ACM4
Muscarinic acetylcholine receptor M4

2

0

High-throughput

0.602

High

580822

PVR
Poliovirus receptor

2

0

High-throughput

0.602

High

733054

VIPR1
Vasoactive intestinal polypeptide receptor 1

2

0

High-throughput

0.602

High

1029628

CD83
CD83 antigen

2

0

High-throughput

0.602

High

981654

RAN
GTP-binding nuclear protein Ran

1

0

Small-scale

0.586

High

683319

TNR5
Tumor necrosis factor receptor superfamily member 5

2

0

High-throughput

0.576

High

1401088

NPTN
Neuroplastin

2

0

High-throughput

0.576

High

133303

P2Y10
Putative P2Y purinoceptor 10

1

4

High-throughput

0.536

High

182738

GP182
G-protein coupled receptor 182

1

5

High-throughput

0.536

High

638504

FPR1
fMet-Leu-Phe receptor

1

5

High-throughput

0.536

High

640453

C5AR1
C5a anaphylatoxin chemotactic receptor 1

1

4

High-throughput

0.536

High

719830

V2R
Vasopressin V2 receptor

1

2

High-throughput

0.536

High

879815

NPY2R
Neuropeptide Y receptor type 2

1

2

High-throughput

0.536

High

914330

EFNA4
Ephrin-A4

1

1

High-throughput

0.536

High

1022939

EFNB1
Ephrin-B1

1

1

High-throughput

0.536

High

1101636

GPR17
Uracil nucleotide/cysteinyl leukotriene receptor

1

3

High-throughput

0.536

High

166396

ZNT4
Probable proton-coupled zinc antiporter SLC30A4

2

0

High-throughput

0.528

High

139587

PESC
Pescadillo homolog

1

0

High-throughput

0.513

High

280949

HYPM
Huntingtin-interacting protein M

1

0

High-throughput

0.513

High

388283

GLPA
Glycophorin-A

1

0

High-throughput

0.513

High

486606

TACD2
Tumor-associated calcium signal transducer 2

1

0

High-throughput

0.513

High

661319

AT2B4
Plasma membrane calcium-transporting ATPase 4

1

0

High-throughput

0.513

High

1093162

STK4
Serine/threonine-protein kinase 4

1

0

High-throughput

0.513

High

1111209

SNW1
SNW domain-containing protein 1

1

0

High-throughput

0.513

High

1132575

FXYD3
FXYD domain-containing ion transport regulator 3

1

0

High-throughput

0.513

High

1249834

BTNL9
Butyrophilin-like protein 9

1

0

High-throughput

0.513

High

1399592

OPALI
Opalin

1

0

High-throughput

0.513

High

1401072

KI2L4
Killer cell immunoglobulin-like receptor 2DL4

1

0

High-throughput

0.513

High

1401074

CCG6
Voltage-dependent calcium channel gamma-6 subunit

1

0

High-throughput

0.513

High

1401079

RASF1
Ras association domain-containing protein 1

1

0

High-throughput

0.513

High

1401083

GPC5D
G-protein coupled receptor family C group 5 member D

1

0

High-throughput

0.513

High

1401085

HCST
Hematopoietic cell signal transducer

1

0

High-throughput

0.513

High

171560

S27A2
Long-chain fatty acid transport protein 2

1

0

High-throughput

0.493

High

891748

GSK3B
Glycogen synthase kinase-3 beta

1

0

High-throughput

0.493

High

1401078

BRF2
Transcription factor IIIB 50 kDa subunit

1

0

High-throughput

0.493

High

1014584

SMAD3
Mothers against decapentaplegic homolog 3

1

0

Small-scale

0.480

High

896615

VASP
Vasodilator-stimulated phosphoprotein

1

1

Small-scale

0.479

High

1164074

PTPRN
Receptor-type tyrosine-protein phosphatase-like N

1

1

High-throughput

0.479

High

1331353

ENAH
Protein enabled homolog

1

1

Small-scale

0.479

High

218652

TGON2
Trans-Golgi network integral membrane protein 2

1

0

High-throughput

0.458

High

252478

DIAP1
Protein diaphanous homolog 1

1

0

Small-scale

0.458

High

363739

EGFR
Epidermal growth factor receptor

1

0

High-throughput

0.458

High

459726

PROF1
Profilin-1

1

0

Small-scale

0.458

High

614724

PTPRA
Receptor-type tyrosine-protein phosphatase alpha

1

0

High-throughput

0.458

High

696267

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

0

High-throughput

0.458

High

768943

RFA3
Replication protein A 14 kDa subunit

1

0

High-throughput

0.458

High

839345

MTOR
Serine/threonine-protein kinase mTOR

1

0

High-throughput

0.458

High

996522

ACTS
Actin, alpha skeletal muscle

1

0

Small-scale

0.458

High

1087960

NFIA
Nuclear factor 1 A-type

1

0

High-throughput

0.458

High

1249135

LMBRL
Protein LMBR1L

1

0

High-throughput

0.458

High

1255147

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.458

High

1401073

LST8
Target of rapamycin complex subunit LST8

1

0

High-throughput

0.458

High

1401077

PKHA4
Pleckstrin homology domain-containing family A member 4

1

0

High-throughput

0.458

High

754082

CD80
T-lymphocyte activation antigen CD80

1

3

High-throughput

0.445

High

771211

APJ
Apelin receptor

1

2

High-throughput

0.445

High

1366188

LPAR1
Lysophosphatidic acid receptor 1

1

2

High-throughput

0.445

High

1401075

S39A8
Metal cation symporter ZIP8

1

1

High-throughput

0.445

High

1401080

S39A9
Zinc transporter ZIP9

1

1

High-throughput

0.445

High

1401082

SCN3B
Sodium channel regulatory subunit beta-3

1

3

High-throughput

0.445

High

530245

TAU
Microtubule-associated protein tau

1

0

High-throughput

0.426

High

1227302

A16L1
Autophagy-related protein 16-1

1

0

High-throughput

0.426

High

1293895

VSIG1
V-set and immunoglobulin domain-containing protein 1

1

1

High-throughput

0.407

High

50672

HACL2
2-hydroxyacyl-CoA lyase 2

3

0

High-throughput

0.345

High

939522

FCGRN
IgG receptor FcRn large subunit p51

2

0

High-throughput

0.328

High

1330736

SIGL1
SIGLEC family-like protein 1

2

0

High-throughput

0.328

High

209096

CYB5B
Cytochrome b5 type B

1

0

High-throughput

0.279

Low

253886

TPST2
Protein-tyrosine sulfotransferase 2

1

0

High-throughput

0.279

Low

932347

ARSF
Arylsulfatase F

1

0

High-throughput

0.279

Low

1291663

CMTD1
Catechol O-methyltransferase domain-containing protein 1

1

0

High-throughput

0.279

Low

1392154

RUSF1
RUS family member 1

1

0

High-throughput

0.279

Low

1401071

SEC62
Translocation protein SEC62

1

0

High-throughput

0.279

Low

1401076

F234A
Protein FAM234A

1

0

High-throughput

0.279

Low

1401081

OCAD1
OCIA domain-containing protein 1

1

0

High-throughput

0.279

Low

1401086

CC018
Uncharacterized protein C3orf18

1

0

High-throughput

0.279

Low

1251552

THADA
tRNA

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025