HitPredict

Interactor 1: ARPC5 (P40518)
Actin-related protein 2/3 complex subunit 5 (Arp2/3 complex 16 kDa subunit) (p16-ARC)
Gene: ARC15

Interactor 2: MYO5 (Q04439)
Myosin-5 (Actin-dependent myosin-I MYO5) (Class I unconventional myosin MYO5) (Type I myosin MYO5)
Gene: MYO5

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.72	0.60	0.658

Property	Details
Experiments	12429847, 18467557, 37968396
Identification Methods	affinity chromatography technology, protein complementation assay, dihydrofolate reductase reconstruction
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0015629 - actin cytoskeleton GO:0030479 - actin cortical patch GO:0051015 - actin filament binding
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 154 Sc			1 1219
+	Sc
		730568 ARPC5_YEAST (1-154): 1.7e-62: 190: 100.00		MYO3_YEAST (1-1205): 0: 1087: 72.08
+	Sp
		1013760 ARPC5_SCHPO (5-151): 5.73e-50: 158: 28.95		MYO1_SCHPO (1-1219): 0: 1043: 51.57
+	Hs
		181299 ARPC5_HUMAN (2-154): 2.34e-57: 177: 25.33		MYH11_HUMAN (5-1118): 0: 1018: 24.03
+	Hs
		728510 ARP5L_HUMAN (1-154): 2.89e-56: 174: 27.74		MYH11_HUMAN (5-1118): 0: 1018: 24.03
+	Hs
		724986 ARP5L_HUMAN (1-154): 2.89e-56: 174: 27.74		MYH9_HUMAN (7-1119): 0: 1017: 23.96