HitPredict

Interactor 1: ARPC5 (P40518)
Actin-related protein 2/3 complex subunit 5 (Arp2/3 complex 16 kDa subunit) (p16-ARC)
Gene: ARC15

Interactor 2: ARPC3 (Q05933)
Actin-related protein 2/3 complex subunit 3 (Arp2/3 complex 21 kDa subunit) (p21-ARC)
Gene: ARC18

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.84 0.60 0.714

The method score is based on:

Property Details
Experiments 11805826, 16183906, 16429126, 18077328, 37968396
Identification Methods tandem affinity purification, biochemical, affinity chromatography technology, fluorescent resonance energy transfer
Interaction Type physical association, association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005885 - Arp2/3 protein complex
GO:0015629 - actin cytoskeleton
GO:0030833 - regulation of actin filament polymerization
GO:0034314 - Arp2/3 complex-mediated actin nucleation
GO:0045010 - actin nucleation
and 2 others

more...
Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 154
Sc

1 178
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024