HitPredict

Interactor 1: URM1 (P40554)
Ubiquitin-related modifier 1
Gene: URM1

Interactor 2: CTU1 (P53088)
Cytoplasmic tRNA 2-thiolation protein 1 (EC 2.7.7.-) (Cytoplasmic tRNA adenylyltransferase 1) (Needs CLA4 to survive protein 6) (Thiolation of uridine in cytoplasmic tRNA protein 1)
Gene: NCS6

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.69	0.60	0.644

Property	Details
Experiments	19145231, 37968396
Identification Methods	two hybrid, anti tag coimmunoprecipitation, tandem affinity purification, affinity chromatography technology
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0002098 - tRNA wobble uridine modification GO:0002143 - tRNA wobble position uridine thiolation GO:0005829 - cytosol GO:0032447 - protein urmylation GO:0034227 - tRNA thio-modification
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1 99 Sc			1 359
+	Hs
		1192569 URM1_HUMAN (2-99): 5.48e-42: 134: 42.42		CTU1_HUMAN (22-344): 1.67e-101: 305: 46.95
+	Hs
		1103445 URM1_HUMAN (2-99): 5.48e-42: 134: 42.42		CTU2_HUMAN (153-311): 6.06e-27: 113: 16.56
+	Sc
		775487 URM1_YEAST (1-99): 5.16e-41: 132: 100.00		CTU2_YEAST (20-320): 1.83e-16: 82.2: 10.57