HitPredict

Interactor 1: ARL1 (P40616)
ADP-ribosylation factor-like protein 1
Gene: ARL1

Interactor 2: GOGA4 (Q13439)
Golgin subfamily A member 4 (256 kDa golgin) (Golgin-245) (Protein 72.1) (Trans-Golgi p230)
Gene: GOLGA4

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.82	1.00	0.908

Property	Details
Experiments	12972563, 11303027, 14580338, 35844135
Identification Methods	two hybrid, x-ray crystallography, pull down, affinity chromatography technology, proximity labelling technology
Interaction Type	direct interaction, association, physical association

Property	Details
Interacting Pfam domains	Arf~GRIP
Common GO terms	GO:0000139 - Golgi membrane GO:0005737 - cytoplasm GO:0005794 - Golgi apparatus GO:0005802 - trans-Golgi network GO:0005829 - cytosol and 1 others more... GO:0016192 - vesicle-mediated transport
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 181 Hs			1 2230
+	Hs
		776117 ARL1_HUMAN (1-181): 6.64e-127: 355: 100.00		GOGB1_HUMAN (1086-2213): 2.91e-28: 127: 10.80
+	Dm
		627119 ARL1_DROME (1-181): 2.14e-97: 281: 78.45		Q9W1R3_DROME (1260-2146): 8.3e-19: 96.3: 13.71
+	Hs
		897361 ARF3_HUMAN (1-181): 1.81e-68: 207: 56.91		GOGB1_HUMAN (1086-2213): 2.91e-28: 127: 10.80
+	Hs
		950493 ARF1_HUMAN (1-181): 3.09e-68: 207: 56.91		GOGB1_HUMAN (1086-2213): 2.91e-28: 127: 10.80
+	Hs
		918867 RAB1A_HUMAN (18-180): 2.69e-66: 203: 22.02		GOGB1_HUMAN (1086-2213): 2.91e-28: 127: 10.80
+	Hs
		950615 ARF5_HUMAN (1-180): 6.4e-67: 203: 58.33		GOGB1_HUMAN (1086-2213): 2.91e-28: 127: 10.80
+	Hs
		148603 ARF3_HUMAN (1-181): 1.81e-68: 207: 56.91		CTRO_HUMAN (163-985): 1.03e-09: 66.2: 21.71
+	Hs
		148636 RAB1A_HUMAN (18-180): 2.69e-66: 203: 22.02		CTRO_HUMAN (163-985): 1.03e-09: 66.2: 21.71
+	Hs
		149274 RAB1B_HUMAN (18-180): 6.06e-66: 202: 23.21		CTRO_HUMAN (163-985): 1.03e-09: 66.2: 21.71