Protein: INT12
Integrator complex subunit 12 (Int12) (PHD finger protein 22)

Gene: INT12, INTS12
Organism: Homo sapiens
Interactions: 107
UniProt ID: Q96CB8

Gene Ontology (top 5):
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0016180 - snRNA processing
GO:0032039 - integrator complex
GO:0034243 - regulation of transcription elongation by RNA polymerase II

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

930952

PP2AA
Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform

4

1

Small-scale

0.699

High

1231104

INT1
Integrator complex subunit 1

3

1

High-throughput

0.657

High

1030408

G3BP1
Ras GTPase-activating protein-binding protein 1

1

0

High-throughput

0.656

High

672234

2AAA
Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform

2

0

High-throughput

0.602

High

726977

FUS
RNA-binding protein FUS

1

0

High-throughput

0.586

High

124039

SPT5H
Transcription elongation factor SPT5

2

0

High-throughput

0.585

High

1062188

HAPR1
HUWE1-associated protein modifying stress responses 1

2

0

High-throughput

0.580

High

623012

EDNRB
Endothelin receptor type B

2

2

High-throughput

0.574

High

723370

APJ
Apelin receptor

2

3

High-throughput

0.574

High

876175

PAR2
Proteinase-activated receptor 2

2

4

High-throughput

0.574

High

370168

ESR1
Estrogen receptor

2

2

High-throughput

0.571

High

1286603

INT6
Integrator complex subunit 6

2

0

Small-scale

0.559

High

1265332

SIA8A
Alpha-N-acetylneuraminide alpha-2,8-sialyltransferase

2

1

High-throughput

0.558

High

1286600

GT2D1
General transcription factor II-I repeat domain-containing protein 1

1

0

Small-scale

0.549

High

915255

PP2AB
Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform

1

1

High-throughput

0.536

High

1286585

INT14
Integrator complex subunit 14

1

1

High-throughput

0.536

High

196646

ZBT24
Zinc finger and BTB domain-containing protein 24

1

0

High-throughput

0.513

High

508654

TOP1
DNA topoisomerase 1

1

0

High-throughput

0.513

High

565127

ZNF8
Zinc finger protein 8

1

0

High-throughput

0.513

High

566782

JUNB
Transcription factor JunB

1

0

High-throughput

0.513

High

583542

RPB3
DNA-directed RNA polymerase II subunit RPB3

1

0

Small-scale

0.513

High

583764

RPAB1
DNA-directed RNA polymerases I, II, and III subunit RPABC1

1

0

High-throughput

0.513

High

589133

TCO2
Transcobalamin-2

1

0

High-throughput

0.513

High

676959

RPB2
DNA-directed RNA polymerase II subunit RPB2

1

0

High-throughput

0.513

High

738865

RPB9
DNA-directed RNA polymerase II subunit RPB9

1

0

High-throughput

0.513

High

854449

RPB11
DNA-directed RNA polymerase II subunit RPB11-a

1

0

High-throughput

0.513

High

864969

RPAB4
DNA-directed RNA polymerases I, II, and III subunit RPABC4

1

0

High-throughput

0.513

High

897593

RPAB2
DNA-directed RNA polymerases I, II, and III subunit RPABC2

1

0

High-throughput

0.513

High

934379

CSK21
Casein kinase II subunit alpha

1

0

High-throughput

0.513

High

976360

PTH1R
Parathyroid hormone/parathyroid hormone-related peptide receptor

1

0

High-throughput

0.513

High

996821

SSRP1
FACT complex subunit SSRP1

1

0

High-throughput

0.513

High

1077250

ZN174
Zinc finger protein 174

1

0

High-throughput

0.513

High

1205793

P66A
Transcriptional repressor p66-alpha

1

0

High-throughput

0.513

High

1260723

NAT14
Probable N-acetyltransferase 14

1

0

High-throughput

0.513

High

1286588

NELFA
Negative elongation factor A

1

0

High-throughput

0.513

High

1286597

FOXJ2
Forkhead box protein J2

1

0

High-throughput

0.513

High

1286604

FZD10
Frizzled-10

1

0

High-throughput

0.513

High

831567

CEBPA
CCAAT/enhancer-binding protein alpha

1

0

High-throughput

0.505

High

172167

GP182
G-protein coupled receptor 182

1

3

High-throughput

0.489

High

198123

MTLR
Motilin receptor

1

3

High-throughput

0.489

High

380141

MAS
Proto-oncogene Mas

1

5

High-throughput

0.489

High

551412

SIAT1
Beta-galactoside alpha-2,6-sialyltransferase 1

1

1

High-throughput

0.489

High

674067

V2R
Vasopressin V2 receptor

1

2

High-throughput

0.489

High

782455

P2RY2
P2Y purinoceptor 2

1

4

High-throughput

0.489

High

895703

CXCR4
C-X-C chemokine receptor type 4

1

3

High-throughput

0.489

High

1031041

GPR17
Uracil nucleotide/cysteinyl leukotriene receptor

1

4

High-throughput

0.489

High

1286584

RNF31
E3 ubiquitin-protein ligase RNF31

1

1

High-throughput

0.489

High

487658

ANDR
Androgen receptor

1

2

High-throughput

0.479

High

935094

H31
Histone H3.1

1

1

High-throughput

0.479

High

952533

H33
Histone H3.3

1

1

High-throughput

0.479

High

1254880

SP7
Transcription factor Sp7

1

1

High-throughput

0.479

High

1269324

ESR2
Estrogen receptor beta

1

2

High-throughput

0.479

High

1286599

ZRAN1
Ubiquitin thioesterase ZRANB1

1

1

High-throughput

0.479

High

205813

TGON2
Trans-Golgi network integral membrane protein 2

1

0

High-throughput

0.458

High

228303

PRKN
E3 ubiquitin-protein ligase parkin

1

0

High-throughput

0.458

High

553391

RFA2
Replication protein A 32 kDa subunit

1

0

High-throughput

0.458

High

632848

TYY1
Transcriptional repressor protein YY1

1

0

High-throughput

0.458

High

651909

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

0

High-throughput

0.458

High

721115

RFA3
Replication protein A 14 kDa subunit

1

0

High-throughput

0.458

High

917719

H4
Histone H4

1

0

High-throughput

0.458

High

1052000

ELOA1
Elongin-A

1

0

Small-scale

0.458

High

1120009

PDCD4
Programmed cell death protein 4

1

0

High-throughput

0.458

High

1148317

INT3
Integrator complex subunit 3

1

0

High-throughput

0.458

High

1160526

INT5
Integrator complex subunit 5

1

0

High-throughput

0.458

High

1188691

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

0

High-throughput

0.458

High

1198262

UBP37
Ubiquitin carboxyl-terminal hydrolase 37

1

0

Small-scale

0.458

High

1286586

DDA1
DET1- and DDB1-associated protein 1

1

0

High-throughput

0.458

High

1286587

KLF16
Krueppel-like factor 16

1

0

High-throughput

0.458

High

1286590

MET14
N6-adenosine-methyltransferase non-catalytic subunit

1

0

High-throughput

0.458

High

1286593

INT10
Integrator complex subunit 10

1

0

Small-scale

0.458

High

1286596

TLS1
Splicing factor C9orf78

1

0

High-throughput

0.458

High

893587

SEM1
26S proteasome complex subunit SEM1

1

0

High-throughput

0.426

High

1039757

SNW1
SNW domain-containing protein 1

1

0

High-throughput

0.426

High

1057576

RRP1B
Ribosomal RNA processing protein 1 homolog B

1

0

High-throughput

0.426

High

1241768

RN169
E3 ubiquitin-protein ligase RNF169

1

0

Small-scale

0.426

High

848926

AL3A2
Aldehyde dehydrogenase family 3 member A2

3

0

High-throughput

0.347

High

1286595

TA2R7
Taste receptor type 2 member 7

3

0

High-throughput

0.347

High

50209

HACL2
2-hydroxyacyl-CoA lyase 2

2

0

High-throughput

0.328

High

1056232

I13R2
Interleukin-13 receptor subunit alpha-2

2

0

High-throughput

0.328

High

1125875

AR13A
ADP-ribosylation factor-like protein 13A

2

0

High-throughput

0.328

High

798269

KI2S2
Killer cell immunoglobulin-like receptor 2DS2

2

0

High-throughput

0.318

High

1224933

FAM9A
Protein FAM9A

2

0

High-throughput

0.316

High

212222

ERD23
ER lumen protein-retaining receptor 3

1

0

High-throughput

0.279

Low

271974

CTAG2
Cancer/testis antigen 2

1

0

High-throughput

0.279

Low

283657

JTB
Protein JTB

1

0

High-throughput

0.279

Low

795378

SSRB
Translocon-associated protein subunit beta

1

0

High-throughput

0.279

Low

856442

EFNA4
Ephrin-A4

1

0

High-throughput

0.279

Low

1153137

TYW3
tRNA wybutosine-synthesizing protein 3 homolog

1

0

High-throughput

0.279

Low

1193271

B3GN8
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 8

1

0

High-throughput

0.279

Low

1202525

CMTD1
Catechol O-methyltransferase domain-containing protein 1

1

0

High-throughput

0.279

Low

1221933

PLPP6
Polyisoprenoid diphosphate/phosphate phosphohydrolase PLPP6

1

0

High-throughput

0.279

Low

1236113

KTAP2
Keratinocyte-associated protein 2

1

0

High-throughput

0.279

Low

1254624

HUMMR
Protein MGARP

1

0

High-throughput

0.279

Low

1286591

GTR9
Solute carrier family 2, facilitated glucose transporter member 9

1

0

High-throughput

0.279

Low

1286592

LIN7C
Protein lin-7 homolog C

1

0

High-throughput

0.279

Low

1286594

OCAD1
OCIA domain-containing protein 1

1

0

High-throughput

0.279

Low

1286598

SLAI2
SLAIN motif-containing protein 2

1

0

High-throughput

0.279

Low

1286601

CTNA3
Catenin alpha-3

1

0

High-throughput

0.279

Low

1286602

DKKL1
Dickkopf-like protein 1

1

0

High-throughput

0.279

Low

216299

CALU
Calumenin

1

0

High-throughput

0.269

Low

395438

A4
Amyloid-beta precursor protein

1

0

High-throughput

0.261

Low

726351

BASI
Basigin

1

0

High-throughput

0.249

Low

982367

1433F
14-3-3 protein eta

1

0

High-throughput

0.249

Low

1030748

SLAF1
Signaling lymphocytic activation molecule

1

0

High-throughput

0.249

Low

1159411

FBX42
F-box only protein 42

1

0

High-throughput

0.249

Low

1173039

SEML
Putative protein SEM1, isoform 2

1

0

High-throughput

0.249

Low

1286589

PKHA4
Pleckstrin homology domain-containing family A member 4

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024