Interactor 1: MLH1 (P40692)
DNA mismatch repair protein Mlh1 (MutL protein homolog 1)
Gene: MLH1

Interactor 2: AP2B1 (P63010)
AP-2 complex subunit beta (AP105B) (Adaptor protein complex AP-2 subunit beta) (Adaptor-related protein complex 2 subunit beta) (Beta-2-adaptin) (Beta-adaptin) (Clathrin assembly protein complex 2 beta large chain) (Plasma membrane adaptor HA2/AP2 adaptin beta subunit)
Gene: AP2B1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.88 0.60 0.728

The method score is based on:

Property Details
Experiments 25910212, 27107012, 16189514, 32296183, unassigned1304
Identification Methods two hybrid, barcode fusion genetics two hybrid, two hybrid bait and prey pooling approach, two hybrid array, validated two hybrid, two hybrid prey pooling approach, two hybrid pooling approach
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0016020 - membrane
Homologous interactions 4

Homologous interactions

Color coding for hit scores

1 756
Hs

1 937
+ Hs
+ Hs
+ Dm
+ Dm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024