HitPredict

Interactor 1: RLP7 (P40693)
Ribosome biogenesis protein RLP7 (Ribosomal protein L7-like)
Gene: RLP7

Interactor 2: HAS1 (Q03532)
ATP-dependent RNA helicase HAS1 (EC 3.6.4.13) (Helicase associated with SET1 protein 1)
Gene: HAS1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.93	0.60	0.748

Property	Details
Experiments	25877921, 30568249, 31511893, 37968396, 23788678, 35615984, 23945946, 24129494, unassigned1262
Identification Methods	two hybrid, affinity chromatography technology, validated two hybrid, two hybrid array
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000463 - maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) GO:0003723 - RNA binding GO:0005730 - nucleolus GO:0030687 - preribosome, large subunit precursor GO:0042273 - ribosomal large subunit biogenesis
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 322 Sc			1 505
+	Sc
		416004 RLP7_YEAST (1-322): 4.14e-115: 337: 100.00		DED1_YEAST (20-418): 1.09e-136: 409: 27.85
+	Sc
		624112 RLP7_YEAST (1-322): 4.14e-115: 337: 100.00		DBP2_YEAST (5-421): 8.67e-134: 400: 29.22
+	Sc
		404491 RL7A_YEAST (68-322): 2.2e-72: 225: 30.20		DBP4_YEAST (3-501): 9.9e-165: 486: 37.70
+	Sc
		593726 RL7B_YEAST (68-322): 3.39e-72: 225: 30.20		DBP4_YEAST (3-501): 9.9e-165: 486: 37.70
+	Sc
		976891 RL7B_YEAST (68-322): 3.39e-72: 225: 30.20		HAS1_YEAST (1-505): 1.8e-165: 479: 100.00
+	Sc
		404502 RL7A_YEAST (68-322): 2.2e-72: 225: 30.20		DBP2_YEAST (5-421): 8.67e-134: 400: 29.22
+	Dm
		1363480 Q9VKC1_DROME (13-320): 2.58e-62: 200: 28.39		DDX18_DROME (8-500): 6.83e-136: 409: 58.59
+	Hs
		1150366 RL7L_HUMAN (16-322): 1.79e-57: 187: 23.78		DDX18_HUMAN (2-492): 3.3e-139: 418: 59.76
+	Sc
		699691 RLP7_YEAST (1-322): 4.14e-115: 337: 100.00		DRS1_YEAST (26-394): 3.8e-72: 245: 38.32
+	Sc
		638780 RLP7_YEAST (1-322): 4.14e-115: 337: 100.00		SPB4_YEAST (56-488): 1.9e-61: 213: 33.41
+	Sc
		404535 RL7A_YEAST (68-322): 2.2e-72: 225: 30.20		DRS1_YEAST (26-394): 3.8e-72: 245: 38.32
+	Hs
		1150360 RL7L_HUMAN (16-322): 1.79e-57: 187: 23.78		DDX31_HUMAN (9-505): 3.72e-82: 274: 32.37
+	Sc
		404483 RL7A_YEAST (68-322): 2.2e-72: 225: 30.20		MS116_YEAST (5-409): 4.69e-64: 221: 35.63
+	Sc
		404513 RL7A_YEAST (68-322): 2.2e-72: 225: 30.20		SPB4_YEAST (56-488): 1.9e-61: 213: 33.41
+	Sc
		638899 RL7B_YEAST (68-322): 3.39e-72: 225: 30.20		SPB4_YEAST (56-488): 1.9e-61: 213: 33.41
+	Hs
		1150339 RL7L_HUMAN (16-322): 1.79e-57: 187: 23.78		DDX27_HUMAN (44-441): 4.37e-71: 243: 37.04