HitPredict

Interactor 1: RBBP7 (Q16576)
Histone-binding protein RBBP7 (Histone acetyltransferase type B subunit 2) (Nucleosome-remodeling factor subunit RBAP46) (Retinoblastoma-binding protein 7) (RBBP-7) (Retinoblastoma-binding protein p46)
Gene: RBBP7

Interactor 2: SP30L (Q9HAJ7)
Histone deacetylase complex subunit SAP30L (HCV non-structural protein 4A-transactivated protein 2) (Sin3 corepressor complex subunit SAP30L) (Sin3-associated protein p30-like)
Gene: SAP30L

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.81	0.60	0.699

The method score is based on:

Property	Details
Experiments	26186194, 28514442, 27705803, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation, tandem affinity purification
Interaction Type	physical association, association

The annotation score is based on:

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000118 - histone deacetylase complex GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006355 - regulation of DNA-templated transcription and 6 others more... GO:0030336 - negative regulation of cell migration GO:0030512 - negative regulation of transforming growth factor beta receptor signaling pathway GO:0031491 - nucleosome binding GO:0042393 - histone binding GO:1902455 - negative regulation of stem cell population maintenance GO:1902459 - positive regulation of stem cell population maintenance
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1	425
Hs

1	183

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024