HitPredict

Interactor 1: RAC1 (P40792)
Ras-related protein Rac1
Gene: RAC1

Interactor 2: Q9V428 (Q9V428)
Icarus, isoform A (Icarus, isoform B) (Icarus, isoform C) (MIP12770p) (RE04081p)
Gene: ics

Species: Drosophila melanogaster

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	26170296
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0007165 - signal transduction
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 192 Dm			1 283
+	Dm
		776889 RAC1_DROME (1-192): 3.66e-81: 240: 100.00		SCRIB_DROME (17-282): 7.11e-53: 187: 21.66
+	Hs
		925273 RAC1_HUMAN (1-192): 2.19e-83: 246: 91.67		SCRIB_HUMAN (2-251): 2.28e-48: 174: 27.20
+	Hs
		894119 CDC42_HUMAN (1-192): 7.64e-77: 229: 69.27		LRCH2_HUMAN (7-252): 8.24e-54: 188: 28.23
+	Hs
		1050061 RHOJ_HUMAN (2-190): 4.27e-80: 239: 60.32		SCRIB_HUMAN (2-251): 2.28e-48: 174: 27.20
+	Hs
		545370 RAC2_HUMAN (1-192): 5.01e-80: 238: 89.06		SCRIB_HUMAN (2-251): 2.28e-48: 174: 27.20
+	Hs
		950989 RHOG_HUMAN (1-192): 2.98e-77: 230: 67.19		SCRIB_HUMAN (2-251): 2.28e-48: 174: 27.20
+	Hs
		893999 CDC42_HUMAN (1-192): 7.64e-77: 229: 69.27		SCRIB_HUMAN (2-251): 2.28e-48: 174: 27.20
+	Hs
		925539 RAC1_HUMAN (1-192): 2.19e-83: 246: 91.67		ERBIN_HUMAN (5-233): 7.39e-42: 155: 25.20
+	Hs
		925519 RAC1_HUMAN (1-192): 2.19e-83: 246: 91.67		LRCH3_HUMAN (5-234): 2.87e-40: 150: 26.41
+	Hs
		1301445 RHOJ_HUMAN (2-190): 4.27e-80: 239: 60.32		ERBIN_HUMAN (5-233): 7.39e-42: 155: 25.20
+	Hs
		545571 RAC2_HUMAN (1-192): 5.01e-80: 238: 89.06		ERBIN_HUMAN (5-233): 7.39e-42: 155: 25.20
+	Hs
		951251 RHOG_HUMAN (1-192): 2.98e-77: 230: 67.19		ERBIN_HUMAN (5-233): 7.39e-42: 155: 25.20
+	Hs
		894337 CDC42_HUMAN (1-192): 7.64e-77: 229: 69.27		ERBIN_HUMAN (5-233): 7.39e-42: 155: 25.20
+	Hs
		894312 CDC42_HUMAN (1-192): 7.64e-77: 229: 69.27		LRCH3_HUMAN (5-234): 2.87e-40: 150: 26.41
+	Hs
		925419 RAC1_HUMAN (1-192): 2.19e-83: 246: 91.67		LRC8A_HUMAN (31-277): 7.39e-17: 82.2: 16.85
+	Hs
		1219415 RHOJ_HUMAN (2-190): 4.27e-80: 239: 60.32		LRC8A_HUMAN (31-277): 7.39e-17: 82.2: 16.85
+	Hs
		545486 RAC2_HUMAN (1-192): 5.01e-80: 238: 89.06		LRC8A_HUMAN (31-277): 7.39e-17: 82.2: 16.85
+	Hs
		925299 RAC1_HUMAN (1-192): 2.19e-83: 246: 91.67		RSU1_HUMAN (3-95): 2.42e-13: 70.1: 19.15
+	Hs
		951139 RHOG_HUMAN (1-192): 2.98e-77: 230: 67.19		LRC8A_HUMAN (31-277): 7.39e-17: 82.2: 16.85
+	Hs
		894196 CDC42_HUMAN (1-192): 7.64e-77: 229: 69.27		LRC8A_HUMAN (31-277): 7.39e-17: 82.2: 16.85