HitPredict

Interactor 1: RFC3 (P40938)
Replication factor C subunit 3 (Activator 1 38 kDa subunit) (A1 38 kDa subunit) (Activator 1 subunit 3) (Replication factor C 38 kDa subunit) (RF-C 38 kDa subunit) (RFC38)
Gene: RFC3

Interactor 2: ATAD5 (Q96QE3)
ATPase family AAA domain-containing protein 5 (Chromosome fragility-associated gene 1 protein)
Gene: ATAD5

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	1.00	0.754

Property	Details
Experiments	31160570, 24981860
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	AAA~DNA_pol3_delta2
Common GO terms	GO:0003677 - DNA binding GO:0005634 - nucleus GO:0016887 - ATP hydrolysis activity GO:0031391 - Elg1 RFC-like complex
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 356 Hs			1 1844
+	Hs
		722022 RFC4_HUMAN (2-345): 2.61e-102: 307: 24.93		ATAD5_HUMAN (1-1844): 0: 1306: 100.00
+	Hs
		777906 RFC5_HUMAN (3-350): 3.32e-93: 283: 24.00		ATAD5_HUMAN (1-1844): 0: 1306: 100.00
+	Hs
		722180 RFC3_HUMAN (1-356): 1.96e-119: 350: 100.00		RFC1_HUMAN (433-1276): 4.59e-53: 207: 14.77
+	Hs
		721934 RFC4_HUMAN (2-345): 2.61e-102: 307: 24.93		RFC1_HUMAN (433-1276): 4.59e-53: 207: 14.77
+	Dm
		725331 Q9U9Q1_DROME (1-349): 2.82e-103: 309: 60.17		RFC1_DROME (609-1293): 8.06e-48: 189: 14.67
+	Hs
		778019 RFC3_HUMAN (1-356): 1.96e-119: 350: 100.00		CTF18_HUMAN (998-1222): 2.17e-34: 146: 17.57
+	Hs
		722068 RFC2_HUMAN (3-341): 1.55e-93: 284: 24.12		RFC1_HUMAN (433-1276): 4.59e-53: 207: 14.77
+	Hs
		722179 RFC5_HUMAN (3-350): 3.32e-93: 283: 24.00		RFC1_HUMAN (433-1276): 4.59e-53: 207: 14.77
+	Dm
		725339 Q9VX15_DROME (2-342): 2.41e-92: 281: 23.78		RFC1_DROME (609-1293): 8.06e-48: 189: 14.67
+	Sp
		195245 RFC5_SCHPO (3-353): 7.25e-92: 280: 49.58		ELG1_SCHPO (730-1251): 1.44e-43: 175: 13.41
+	Hs
		722015 RFC4_HUMAN (2-345): 2.61e-102: 307: 24.93		CTF18_HUMAN (998-1222): 2.17e-34: 146: 17.57
+	Ce
		1090164 Q18547_CAEEL (1-343): 4.12e-93: 283: 52.74		Q18841_CAEEL (778-1293): 4.07e-39: 160: 16.35
+	Sc
		772422 RFC2_YEAST (3-342): 1.14e-92: 282: 23.10		CTF18_YEAST (1020-1501): 1.12e-36: 152: 16.03
+	Hs
		722134 RFC2_HUMAN (3-341): 1.55e-93: 284: 24.12		CTF18_HUMAN (998-1222): 2.17e-34: 146: 17.57
+	Hs
		777901 RFC5_HUMAN (3-350): 3.32e-93: 283: 24.00		CTF18_HUMAN (998-1222): 2.17e-34: 146: 17.57
+	Sc
		751312 RFC2_YEAST (3-342): 1.14e-92: 282: 23.10		RFC1_YEAST (711-1292): 1.4e-34: 146: 14.55
+	Zm
		75542 B4FJC2_MAIZE (2-350): 8.61e-93: 283: 24.72		B4FQT5_MAIZE (1085-1380): 3.28e-31: 128: 14.52
+	Hs
		721989 RFC4_HUMAN (2-345): 2.61e-102: 307: 24.93		MDC1_HUMAN (10-849): 1.46e-20: 101: 8.33
+	Hs
		722109 RFC2_HUMAN (3-341): 1.55e-93: 284: 24.12		MDC1_HUMAN (10-849): 1.46e-20: 101: 8.33
+	Hs
		777860 RFC5_HUMAN (3-350): 3.32e-93: 283: 24.00		MDC1_HUMAN (10-849): 1.46e-20: 101: 8.33