Protein: RAB5B
Ras-related protein Rab-5B (EC 3.6.5.2)

Gene: RAB5B
Organism: Homo sapiens
Interactions: 95
UniProt ID: P61020

Gene Ontology (top 5):
GO:0003924 - GTPase activity
GO:0003925 - G protein activity
GO:0005525 - GTP binding
GO:0005768 - endosome
GO:0005769 - early endosome

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

678339

GDIA
Rab GDP dissociation inhibitor alpha

4

20

High-throughput

0.909

High

895358

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

4

10

Small-scale

0.902

High

545095

PVR
Poliovirus receptor

2

10

High-throughput

0.811

High

592184

RAB5A
Ras-related protein Rab-5A

1

18

High-throughput

0.691

High

622572

RAE1
Rab proteins geranylgeranyltransferase component A 1

1

20

High-throughput

0.691

High

838618

GDIB
Rab GDP dissociation inhibitor beta

1

20

High-throughput

0.691

High

895367

FNDC5
Fibronectin type III domain-containing protein 5

1

6

High-throughput

0.691

High

895370

RAB2B
Ras-related protein Rab-2B

1

19

High-throughput

0.691

High

895385

PKHJ1
Pleckstrin homology domain-containing family J member 1

1

13

High-throughput

0.691

High

895368

RIN3
Ras and Rab interactor 3

1

20

Small-scale

0.680

High

895371

RIN2
Ras and Rab interactor 2

1

20

Small-scale

0.680

High

787362

PK3CB
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform

1

16

Small-scale

0.647

High

883140

HUNK
Hormonally up-regulated neu tumor-associated kinase

1

6

High-throughput

0.625

High

844852

RAB7A
Ras-related protein Rab-7a

1

18

Small-scale

0.621

High

895350

RIN1
Ras and Rab interactor 1

1

20

Small-scale

0.621

High

895374

SGSM3
Small G protein signaling modulator 3

1

17

Small-scale

0.621

High

319779

HERC2
E3 ubiquitin-protein ligase HERC2

1

2

Small-scale

0.618

High

373977

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

14

High-throughput

0.618

High

436233

RHOC
Rho-related GTP-binding protein RhoC

1

20

High-throughput

0.618

High

893850

CDC42
Cell division control protein 42 homolog

1

20

High-throughput

0.618

High

895343

RHOA
Transforming protein RhoA

1

20

High-throughput

0.618

High

895344

RHOB
Rho-related GTP-binding protein RhoB

1

20

High-throughput

0.618

High

895380

PKHA4
Pleckstrin homology domain-containing family A member 4

1

18

High-throughput

0.618

High

895386

ZRAN1
Ubiquitin thioesterase ZRANB1

1

6

High-throughput

0.618

High

895388

NUFP1
FMR1-interacting protein NUFIP1

3

1

High-throughput

0.609

High

895366

FHI1B
FHF complex subunit HOOK-interacting protein 1B

1

5

High-throughput

0.589

High

895348

OCRL
Inositol polyphosphate 5-phosphatase OCRL

1

15

High-throughput

0.575

High

793721

GLP1R
Glucagon-like peptide 1 receptor

1

1

Small-scale

0.561

High

895369

TBC15
TBC1 domain family member 15

1

20

Small-scale

0.555

High

895381

TBC17
TBC1 domain family member 17

1

20

Small-scale

0.555

High

895361

TRI67
Tripartite motif-containing protein 67

1

14

High-throughput

0.553

High

895354

EEA1
Early endosome antigen 1

1

9

Small-scale

0.552

High

125990

UPK1A
Uroplakin-1a

1

1

High-throughput

0.536

High

156816

FFAR1
Free fatty acid receptor 1

1

6

High-throughput

0.536

High

168373

SCAM1
Secretory carrier-associated membrane protein 1

1

20

High-throughput

0.536

High

168526

SCAM2
Secretory carrier-associated membrane protein 2

1

20

High-throughput

0.536

High

351152

TGFA
Protransforming growth factor alpha [Cleaved into: Transforming growth factor alpha

1

1

High-throughput

0.536

High

528870

CFTR
Cystic fibrosis transmembrane conductance regulator

1

6

High-throughput

0.536

High

565906

AATC
Aspartate aminotransferase, cytoplasmic

1

1

High-throughput

0.536

High

574286

RL35A
Large ribosomal subunit protein eL33

1

1

High-throughput

0.536

High

686629

CCR1
C-C chemokine receptor type 1

1

3

High-throughput

0.536

High

882713

STX17
Syntaxin-17

1

2

High-throughput

0.536

High

895377

PLCA
1-acyl-sn-glycerol-3-phosphate acyltransferase alpha

1

4

High-throughput

0.536

High

895379

TX101
Testis-expressed protein 101

1

5

High-throughput

0.536

High

779131

CCNF
Cyclin-F

2

2

High-throughput

0.533

High

791440

HD
Huntingtin

1

8

High-throughput

0.515

High

895349

DYR1A
Dual specificity tyrosine-phosphorylation-regulated kinase 1A

1

7

High-throughput

0.514

High

895390

CC018
Uncharacterized protein C3orf18

1

0

High-throughput

0.513

High

895394

FIS1
Mitochondrial fission 1 protein

1

0

High-throughput

0.513

High

895346

2ABB
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform

1

4

High-throughput

0.489

High

895357

CR021
UPF0711 protein C18orf21

1

1

High-throughput

0.489

High

895372

SARAF
Store-operated calcium entry-associated regulatory factor

1

1

High-throughput

0.489

High

895382

MBNL1
Muscleblind-like protein 1

1

1

High-throughput

0.489

High

895384

CENPM
Centromere protein M

1

2

High-throughput

0.489

High

895392

SSUH2
Protein SSUH2 homolog

1

1

High-throughput

0.489

High

895395

WIF1
Wnt inhibitory factor 1

1

3

High-throughput

0.489

High

895360

APOA5
Apolipoprotein A-V

1

4

High-throughput

0.481

High

895389

PRAF1
Prenylated Rab acceptor protein 1

1

20

High-throughput

0.481

High

390806

RPN2
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2

1

4

High-throughput

0.479

High

501901

BIP
Endoplasmic reticulum chaperone BiP

1

7

High-throughput

0.479

High

503795

HSP7C
Heat shock cognate 71 kDa protein

1

4

High-throughput

0.479

High

803469

BAG6
Large proline-rich protein BAG6

1

9

Small-scale

0.479

High

895353

CUL7
Cullin-7

1

7

High-throughput

0.479

High

895359

FTM
Protein fantom

1

10

High-throughput

0.479

High

895362

CNTRL
Centriolin

1

10

High-throughput

0.479

High

895365

TM192
Transmembrane protein 192

1

1

High-throughput

0.479

High

895373

OPTN
Optineurin

1

19

High-throughput

0.479

High

239889

HCN1
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1

1

5

High-throughput

0.445

High

390159

RPN1
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1

1

4

High-throughput

0.445

High

496695

TAU
Microtubule-associated protein tau

1

15

High-throughput

0.445

High

895351

CAC1C
Voltage-dependent L-type calcium channel subunit alpha-1C

1

5

High-throughput

0.445

High

895347

REEP5
Receptor expression-enhancing protein 5

1

1

High-throughput

0.439

High

895387

SUN2
SUN domain-containing protein 2

1

4

High-throughput

0.439

High

165959

PER2
Period circadian protein homolog 2

1

1

Small-scale

0.437

High

267977

EED
Polycomb protein EED

1

9

High-throughput

0.437

High

329568

AGR2
Anterior gradient protein 2 homolog

1

7

High-throughput

0.437

High

346378

MYC
Myc proto-oncogene protein

1

6

High-throughput

0.437

High

552386

RFA2
Replication protein A 32 kDa subunit

1

8

High-throughput

0.437

High

650833

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

8

High-throughput

0.437

High

720118

RFA3
Replication protein A 14 kDa subunit

1

7

High-throughput

0.437

High

895345

RNF4
E3 ubiquitin-protein ligase RNF4

1

6

High-throughput

0.437

High

895352

TRI25
E3 ubiquitin/ISG15 ligase TRIM25

1

16

High-throughput

0.437

High

895355

EZH2
Histone-lysine N-methyltransferase EZH2

1

4

High-throughput

0.437

High

895356

DUS6
Dual specificity protein phosphatase 6

1

8

High-throughput

0.437

High

895363

TMM17
Transmembrane protein 17

1

1

High-throughput

0.437

High

895364

CEP97
Centrosomal protein of 97 kDa

1

9

High-throughput

0.437

High

895375

NEUL4
Neuralized-like protein 4

1

1

Small-scale

0.437

High

895378

DUS9
Dual specificity protein phosphatase 9

1

8

High-throughput

0.437

High

473112

OST4
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 4

1

2

High-throughput

0.407

High

895391

PPM1H
Protein phosphatase 1H

1

6

Small-scale

0.407

High

895393

FCF1
rRNA-processing protein FCF1 homolog

2

0

High-throughput

0.328

High

303677

OR2A4
Olfactory receptor 2A4

1

0

High-throughput

0.279

Low

319532

LY86
Lymphocyte antigen 86

1

0

High-throughput

0.279

Low

895376

CC85A
Coiled-coil domain-containing protein 85A

1

0

High-throughput

0.279

Low

895383

DPOE3
DNA polymerase epsilon subunit 3

1

0

High-throughput

0.279

Low


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Last updated: 15 Jul 2024