Protein: PHLB1
Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha)

Gene: PHLB1, PHLDB1
Organism: Homo sapiens
Interactions: 54
UniProt ID: Q86UU1

Gene Ontology (top 5):
GO:0045180 - basal cortex
GO:0070507 - regulation of microtubule cytoskeleton organization
GO:0071711 - basement membrane organization

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

374024

RASN
GTPase NRas

2

20

High-throughput

0.675

High

375675

RASK
GTPase KRas

2

20

High-throughput

0.675

High

1289061

PHLB1
Pleckstrin homology-like domain family B member 1

1

17

High-throughput

0.618

High

900396

FXR2
RNA-binding protein FXR2

3

16

High-throughput

0.597

High

854138

KI67
Proliferation marker protein Ki-67

1

20

High-throughput

0.595

High

1006513

SRPK2
SRSF protein kinase 2

1

20

High-throughput

0.579

High

971722

1433E
14-3-3 protein epsilon

2

10

High-throughput

0.558

High

990432

1433Z
14-3-3 protein zeta/delta

2

20

High-throughput

0.558

High

302879

CIAO1
Probable cytosolic iron-sulfur protein assembly protein CIAO1

1

19

High-throughput

0.553

High

374719

RASH
GTPase HRas

1

20

High-throughput

0.553

High

412189

NTRK1
High affinity nerve growth factor receptor

1

20

High-throughput

0.553

High

648572

FGFR4
Fibroblast growth factor receptor 4

1

20

High-throughput

0.553

High

710339

EPHA2
Ephrin type-A receptor 2

1

20

High-throughput

0.553

High

1226985

A16L1
Autophagy-related protein 16-1

1

18

High-throughput

0.553

High

1289072

ANLN
Anillin

1

16

High-throughput

0.553

High

900013

FXR1
RNA-binding protein FXR1

1

16

High-throughput

0.532

High

1289065

SH3K1
SH3 domain-containing kinase-binding protein 1

2

20

High-throughput

0.521

High

250282

VINEX
Vinexin

1

20

High-throughput

0.514

High

1007725

RAE1L
mRNA export factor RAE1

1

11

High-throughput

0.514

High

890853

TSC2
Tuberin

1

13

High-throughput

0.494

High

1289064

TSC1
Hamartin

1

20

High-throughput

0.494

High

1289068

SHAN3
SH3 and multiple ankyrin repeat domains protein 3

1

19

High-throughput

0.494

High

347783

BAG3
BAG family molecular chaperone regulator 3

1

5

High-throughput

0.489

High

1289071

EGLN3
Prolyl hydroxylase EGLN3

1

1

High-throughput

0.489

High

982985

RS25
Small ribosomal subunit protein eS25

1

1

High-throughput

0.470

High

173014

XPO1
Exportin-1

1

12

High-throughput

0.437

High

358730

LDHA
L-lactate dehydrogenase A chain

1

4

High-throughput

0.437

High

372455

MYC
Myc proto-oncogene protein

1

13

High-throughput

0.437

High

404177

GCR
Glucocorticoid receptor

1

20

High-throughput

0.437

High

691191

1433T
14-3-3 protein theta

1

20

High-throughput

0.437

High

730011

1433B
14-3-3 protein beta/alpha

1

20

High-throughput

0.437

High

730726

1433S
14-3-3 protein sigma

1

20

High-throughput

0.437

High

845704

MUC18
Cell surface glycoprotein MUC18

1

15

High-throughput

0.437

High

966551

1433G
14-3-3 protein gamma

1

20

High-throughput

0.437

High

986536

PPIA
Peptidyl-prolyl cis-trans isomerase A

1

11

High-throughput

0.437

High

1049503

1433F
14-3-3 protein eta

1

20

High-throughput

0.437

High

1159727

OCLN
Occludin

1

5

High-throughput

0.437

High

1254461

TRI67
Tripartite motif-containing protein 67

1

20

High-throughput

0.437

High

1289062

ZCH18
Zinc finger CCCH domain-containing protein 18

1

20

High-throughput

0.437

High

1289063

FBX22
F-box only protein 22

1

2

High-throughput

0.437

High

1289069

CCDC8
Coiled-coil domain-containing protein 8

1

11

High-throughput

0.437

High

1289070

GAN
Gigaxonin

1

11

High-throughput

0.437

High

1289074

XPO7
Exportin-7

1

8

High-throughput

0.437

High

1289076

TRRAP
Transformation/transcription domain-associated protein

1

10

High-throughput

0.437

High

347146

BAG2
BAG family molecular chaperone regulator 2

1

4

High-throughput

0.407

High

391320

FRIL
Ferritin light chain

1

4

High-throughput

0.407

High

934810

TERA
Transitional endoplasmic reticulum ATPase

1

14

High-throughput

0.407

High

1054191

P2R3A
Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit alpha

1

1

High-throughput

0.407

High

1288889

RIMS1
Regulating synaptic membrane exocytosis protein 1

1

20

High-throughput

0.407

High

1289066

CK5P2
CDK5 regulatory subunit-associated protein 2

1

20

High-throughput

0.407

High

1289073

DDX28
Probable ATP-dependent RNA helicase DDX28

1

17

High-throughput

0.407

High

1289075

PNMA2
Paraneoplastic antigen Ma2

1

11

High-throughput

0.407

High

1289067

PHAF1
Phagosome assembly factor 1

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025