HitPredict

Interactor 1: ARF6 (P40946)
ADP-ribosylation factor 6 (ARF6) (ADP ribosylation factor at 51F) (ADP-ribosylation factor 3)
Gene: ARF6

Interactor 2: Q9W329 (Q9W329)
Golgi-localized, gamma-adaptin ear containing, ARF binding protein (Golgi-localizing gamma-ear-containing ARF-binding protein) (LD41311p)
Gene: Gga

Species: Drosophila melanogaster

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.48	0.60	0.541

Property	Details
Experiments	15710747
Identification Methods	two hybrid, two hybrid fragment pooling approach
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0006886 - intracellular protein transport GO:0016192 - vesicle-mediated transport
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 175 Dm			1 660
+	Rn
		88618 ARF6_RAT (1-174): 1.22e-67: 205: 97.13		D3ZHG8_RAT (1-643): 1.59e-129: 398: 22.56
+	Rn
		88617 ARF3_RAT (2-174): 1.73e-65: 199: 69.94		D3ZHG8_RAT (1-643): 1.59e-129: 398: 22.56
+	Hs
		950740 ARF5_HUMAN (2-173): 6.17e-69: 208: 65.12		GGA1_HUMAN (5-643): 1.26e-115: 362: 23.33
+	Hs
		913175 ARF6_HUMAN (1-174): 1.22e-67: 205: 97.13		GGA1_HUMAN (5-643): 1.26e-115: 362: 23.33
+	Hs
		950575 ARF1_HUMAN (1-174): 1.64e-67: 205: 67.42		GGA1_HUMAN (5-643): 1.26e-115: 362: 23.33
+	Hs
		913149 ARF6_HUMAN (1-174): 1.22e-67: 205: 97.13		GGA3_HUMAN (1-643): 3.53e-113: 358: 21.64
+	Hs
		950568 ARF1_HUMAN (1-174): 1.64e-67: 205: 67.42		GGA3_HUMAN (1-643): 3.53e-113: 358: 21.64
+	Hs
		897416 ARF3_HUMAN (2-174): 1.73e-65: 199: 69.94		GGA1_HUMAN (5-643): 1.26e-115: 362: 23.33
+	Hs
		897409 ARF3_HUMAN (2-174): 1.73e-65: 199: 69.94		GGA3_HUMAN (1-643): 3.53e-113: 358: 21.64
+	Hs
		574772 ARF4_HUMAN (1-173): 9.05e-71: 213: 64.74		GGA2_HUMAN (5-644): 1.58e-103: 329: 20.46
+	Hs
		913174 ARF6_HUMAN (1-174): 1.22e-67: 205: 97.13		GGA2_HUMAN (5-644): 1.58e-103: 329: 20.46
+	Hs
		950574 ARF1_HUMAN (1-174): 1.64e-67: 205: 67.42		GGA2_HUMAN (5-644): 1.58e-103: 329: 20.46
+	Hs
		897415 ARF3_HUMAN (2-174): 1.73e-65: 199: 69.94		GGA2_HUMAN (5-644): 1.58e-103: 329: 20.46
+	Hs
		277049 ARF5_HUMAN (2-173): 6.17e-69: 208: 65.12		STAM2_HUMAN (4-549): 1.42e-80: 266: 11.59
+	Sc
		580871 ARF2_YEAST (2-174): 1.66e-65: 200: 66.47		GGA1_YEAST (3-421): 3.82e-63: 221: 19.33
+	Sc
		503143 ARF1_YEAST (2-174): 5.83e-65: 198: 66.47		GGA1_YEAST (3-421): 3.82e-63: 221: 19.33
+	Hs
		212615 ARF6_HUMAN (1-174): 1.22e-67: 205: 97.13		AP1G1_HUMAN (430-639): 8.25e-53: 196: 17.34
+	Hs
		212618 ARF1_HUMAN (1-174): 1.64e-67: 205: 67.42		AP1G1_HUMAN (430-639): 8.25e-53: 196: 17.34
+	Sc
		580855 ARF2_YEAST (2-174): 1.66e-65: 200: 66.47		GGA2_YEAST (252-642): 3.06e-14: 78.2: 12.32
+	Sc
		503089 ARF1_YEAST (2-174): 5.83e-65: 198: 66.47		GGA2_YEAST (252-642): 3.06e-14: 78.2: 12.32