HitPredict

Interactor 1: CRK (P46108)
Adapter molecule crk (Proto-oncogene c-Crk) (p38)
Gene: CRK

Interactor 2: TRI39 (Q9HCM9)
E3 ubiquitin-protein ligase TRIM39 (EC 2.3.2.27) (RING finger protein 23) (RING-type E3 ubiquitin transferase TRIM39) (Testis-abundant finger protein) (Tripartite motif-containing protein 39)
Gene: TRIM39

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	17474147
Identification Methods	peptide array
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 304 Hs			1 518
+	Hs
		924879 GRB2_HUMAN (135-297): 2.78e-25: 102: 15.67		TRI39_HUMAN (1-518): 1.69e-173: 501: 100.00
+	Hs
		557799 NCK1_HUMAN (2-100): 1.55e-10: 63.3: 18.00		TRI39_HUMAN (1-518): 1.69e-173: 501: 100.00
+	Hs
		802723 CRK_HUMAN (1-304): 7.82e-68: 215: 100.00		TRI15_HUMAN (15-502): 4.4e-96: 301: 30.10
+	Mm
		1143604 PLCG2_MOUSE (11-301): 1.34e-25: 108: 16.40		TRI27_MOUSE (15-518): 3.72e-136: 405: 37.08
+	Hs
		275202 GRAP2_HUMAN (1-296): 5.17e-33: 125: 17.17		TRI68_HUMAN (16-518): 7.07e-130: 388: 35.45
+	Hs
		536781 GRB2_HUMAN (135-297): 2.78e-25: 102: 15.67		TRI27_HUMAN (15-518): 7.9e-137: 407: 37.28
+	Hs
		584954 GRAP_HUMAN (135-294): 3.79e-21: 91.4: 16.67		RO52_HUMAN (15-513): 3.5e-141: 417: 38.92
+	Hs
		208986 NCK2_HUMAN (2-100): 3.06e-11: 65.2: 18.00		TRI27_HUMAN (15-518): 7.9e-137: 407: 37.28
+	Hs
		1078906 ITSN1_HUMAN (150-302): 3.02e-10: 63.3: 13.87		TRIM5_HUMAN (17-515): 4.67e-108: 332: 28.11
+	Hs
		209157 NCK2_HUMAN (2-100): 3.06e-11: 65.2: 18.00		TRI15_HUMAN (15-502): 4.4e-96: 301: 30.10
+	Hs
		209130 NCK2_HUMAN (2-100): 3.06e-11: 65.2: 18.00		TRI41_HUMAN (11-57): 8.66e-14: 75.9: 48.94