Interactor 1: MSH4 (P40965)
MutS protein homolog 4
Gene: MSH4

Interactor 2: MSH5 (Q12175)
MutS protein homolog 5
Gene: MSH5

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.77 1.00 0.882

The method score is based on:

Property Details
Experiments 9374523, 11283351, 34214491
Identification Methods two hybrid, coimmunoprecipitation, two hybrid pooling approach, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains MutS_II~MutS_III, MutS_II~MutS_V, MutS_III~MutS_III, MutS_III~MutS_V, MutS_V~MutS_V
Common GO terms GO:0000228 - nuclear chromosome
GO:0005524 - ATP binding
GO:0005634 - nucleus
GO:0007131 - reciprocal meiotic recombination
GO:0030983 - mismatched DNA binding
and 2 others

more...

Homologous interactions 14

Homologous interactions

Color coding for hit scores

1 878
Sc

1 901
+ Hs
+ Mm
+ Hs
+ Hs
+ Dr
+ At
+ At
+ Sc
+ Sc
+ Hs
+ Sc
+ Ce
+ Ec
+ At

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Last updated: 15 Jul 2024