Interactor 1: LCB2 (P40970)
Serine palmitoyltransferase 2 (SPT 2) (EC 2.3.1.50) (Long chain base biosynthesis protein 2)
Gene: LCB2

Interactor 2: ORM2 (Q06144)
Protein ORM2
Gene: ORM2

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.88 1.00 0.943

The method score is based on:

Property Details
Experiments 20212121, 20182505, 31133554, 31368600, 30529276, 23363605
Identification Methods pull down, anti tag coimmunoprecipitation, affinity chromatography technology
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Aminotran_1_2~ORMDL
Common GO terms GO:0005783 - endoplasmic reticulum
GO:0030148 - sphingolipid biosynthetic process
GO:0090156 - intracellular sphingolipid homeostasis
Homologous interactions 8

Homologous interactions

Color coding for hit scores

1 561
Sc

1 216
+ Sc
+ Sc
+ Sc
+ At
+ At
+ Hs
+ Hs
+ Hs

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Last updated: 15 Jul 2024